Buch, Englisch, 306 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 499 g
Buch, Englisch, 306 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 499 g
ISBN: 978-1-4899-7345-0
Verlag: Springer US
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
- Naturwissenschaften Biowissenschaften Zellbiologie
Weitere Infos & Material
Basic Aspects of Protein Degradation Through the Ubiquitin Proteasome System (UPS).- Yeast Proteasome Structure and Biogenesis.- Ubiquitin-Proteasome System in the Central Nervous System.- Protein Aggregation, Inclusion Formation and Ups Function.- Protein Aggregation and the UPS: A Two-Way Street.- The Impact of Inclusion Formation on Cell Survival.- Inclusion Formation and Disolution Following Proteasomal Inhibition in Neuronal Cells.- Oxidative Stress and Ups Function.- The Proteasome: Source and a Target of Oxidative Stress?.- Inflammation as a Mediator of Oxidative Stress and UPS Dysfunction.- Proteasome and Neuronal Cell Death and Survival.- Role of the Ubiquitin Proteasome System During Neuronal Cell Death.- Pathways of Neuronal Cell Death Induced by Proteasomal Inhibition.- Models of Dysfunction of the UPS and the Proteasome.- Pharmacological and Molecular Models of Proteasomal Dysfunction.- The Gad Mouse: A Window Into UPS-Related Neurodegeneration and the Function of the Function of the Deubiquitinating Enzyme Uch-L1.- The UPS in Neurodegenerative Diseases and Aging.- Parkinson’s Disease and Related Disorders.- Ubiquitination by Parkin — Implications in Parkinson’s Disease.- The Ups in Neurodegenerative Diseases and Aging Huntington’s Disease.- Frameshift Mutant Ubiquitin in Alzheimer’s Disease and Other Neurodegenerative Disorders.- Motor Neuron Disease.- The Paradoxical Role of Proteasomes in Prion Disorders.- Aging and the Proteasome.