Buch, Englisch, 113 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 201 g
Buch, Englisch, 113 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 201 g
Reihe: SpringerBriefs in Applied Sciences and Technology
ISBN: 978-981-4021-95-1
Verlag: Springer Nature Singapore
This Brief provides the basic knowledge regarding Trisomy 21 diseases and its existing detection methods. The restrictions and disadvantages of each method are discussed accordingly. Therefore, a non-invasive early detection method using 3D ultrasound reconstruction of Nuchal Translucency is introduced. This new method for 3D NT assessments has an edge over the previous 2D methods, and entails the composite function in visualizing the explicit internal marker structure. Further, image processing techniques covered from data acquisition, pre-processing, speckle noise reduction and 3D segmentation are also discussed. This should be especially useful for students and professional researchers in the Biomedical and image processing fields.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
- Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
- Technische Wissenschaften Sonstige Technologien | Angewandte Technik Signalverarbeitung, Bildverarbeitung, Scanning
- Mathematik | Informatik EDV | Informatik Informatik Bildsignalverarbeitung
Weitere Infos & Material
1 Introduction
1.1 Background of Research
1.2 Problem Statement
1.3 Objectives
1.4 Scope of Project
1.5 Contribution of Book
2 Medicine and Engineering Related Researches on the Utility of
Two Dimensional Nuchal Translucency
2.1 Review of Trisomy 21
2.2 History of Trisomy 21 Detection
2.3 Maternal Age Factor
2.4 Effect of Previous Pregnancies Factor
2.5 Existing Detection Methods of Trisomy 21
2.5.1 Ultrasound
2.5.2 Maternal Serum Markers
2.5.3 Genetic Testing
2.5.4 Summary
2.6 Two Dimensional Nuchal Translucency
2.6.1 Medicine Review and Related Researches
2.6.1.1 Existing Limitation
2.6.2 Engineering Review and Related Researches
2.6.2.1 Summary
2.7 Three Dimensional Ultrasound Applications
2.7.1 Summary
3 Designs and Implementation of Three Dimensional Nuchal Translucency
3.1 Introduction
3.2 Data Acquisition
3.3 DICOM and Clips Storage
3.4 3D NT Reconstruction and Visualization
3.4.1 3D Scanning Acquisitions
3.4.2 3D Volume Rendering
3.4.2.1 Virtual Slider Extraction Designs
3.4.2.2 VTK Widget Event Handling Mechanism
3.5 3D Nuchal Translucency Segmentation
3.5.1 Preprocessing 3D Diffusion 3.5.2 3D Seeded Region-Based Segmentation
3.5.3 3D NT in Vivo Measurement
4 Clinical Tests and Measurements
4.1 Introduction
4.2 Descriptive Analysis
4.3 Intra-Observer Variability
4.4 Level Agreement between Measurements
4.4.1 Paired Sample t-test
4.5 Method Repeatability
4.6 Summary
4.7 Discussion
4.7.1 Advantages and Disadvantages of Early Fetal
Abnormalities Detection
5 Future Improvements
5.1 Conclusions
5.2 Limitations and Recommendations