Buch, Englisch, 177 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 300 g
Potential Therapeutic Approaches
Buch, Englisch, 177 Seiten, Paperback, Format (B × H): 155 mm x 235 mm, Gewicht: 300 g
Reihe: Stem Cell Biology and Regenerative Medicine
ISBN: 978-3-030-07457-9
Verlag: Springer International Publishing
The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing cliniciansand advanced graduate students.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin
- Interdisziplinäres Wissenschaften Wissenschaften: Forschung und Information Forschungsmethodik, Wissenschaftliche Ausstattung
- Naturwissenschaften Chemie Chemie Allgemein Pharmazeutische Chemie, Medizinische Chemie
- Naturwissenschaften Biowissenschaften Zellbiologie
Weitere Infos & Material
Autophagy and Stem cells.- Fine-Tuning the Stem Cell Fate by Autophagy.- Role of Autophagy in Aging of Hematopoietic Stem Cells and Their Niche: Relevance in Clinical Transplantations and Regenerative Medicine.- Forkhead box O (FoxO) Transcription Factors in Autophagy, Metabolic Health, and Tissue Homeostasis.- The Role of mTOR in Osteoclasts.- Apoptotic Cell Clearance in Gut Tissue-Role of Intestinal Regeneration.- Autophagic Regulation of Cardiomyocyte Survival and Heart Regeneration.- The Role of Autophagy in Mesenchymal Stem Cell-Based Suppression of Immune Response.- Emerging Connections: Presynaptic Autophagy in Brain Aging and Neurodegenerative Diseases.- Virus and Autophagy: Enemies or Allies.- Cancer Stem Cells and Autophagy: Present Knowledge and Future Perspectives.