Buch, Englisch, 253 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 646 g
Buch, Englisch, 253 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 646 g
Reihe: Molecular Biology Intelligence Unit
ISBN: 978-0-306-47441-5
Verlag: Springer US
The volume offers insight into the key research topics that involve caspases. Leading experts from various areas of biology and medicine have compiled this volume so that both the novice and the professional will use this as the main reference for caspases for years to come. The reader will learn about the role of caspases in apoptosis signaling, inflammation and cancer therapy while being updated on the methodology used to study caspases and the efforts of pharmaceutical research in targeting caspases.
Zielgruppe
Research
Autoren/Hrsg.
Fachgebiete
- Naturwissenschaften Biowissenschaften Biowissenschaften
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Public Health, Gesundheitsmanagement, Gesundheitsökonomie, Gesundheitspolitik
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
- Naturwissenschaften Biowissenschaften Biochemie (nichtmedizinisch)
Weitere Infos & Material
Preface. 1. The Caspase Family 2. Caspase Cascades in Apoptosis 3. Caspase Activation at the TNF-R Family Members Death Inducing Signaling Complexes (DISCs 4. Mitochondrial/Apoptosome Dependent Activation of Caspases 5. Modulation of Caspase Activity by Cellular Inhibitors 6. Virus-Encoded Caspase Inhibitors 7. Apoptosis Dependent and Independent Functions of Caspases 8. the Role of Caspases in Modulation of Cytokines and Other Molecules in Apoptosis and Inflammation 9. Caspases, Bcl-2 Family Proteins and Other Components of the Death Machinery: Their Role in the Regulation of the Immune Response 10. Learning from Deficiency: Gene Targeting of Caspases 11. Caspase Activation in Cancer Therapy 12. In Situ Activation of Caspases Revealed by Affinity Labeling Their Enzymatic Sites13. Other Methods of Caspase Activity Monitoring 14. Caspases as Targets for Drug Development 15. Caspase-Independent Cell Death Mechanisms Index.
