Walsh Biopharmaceuticals

Biochemistry and Biotechnology
2. Auflage 2013
ISBN: 978-1-118-68738-3
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 544 Seiten, E-Book

The latest edition of this highly acclaimed textbook, provides acomprehensive and up-to-date overview of the science and medicalapplications of biopharmaceutical products. Biopharmaceuticalsrefers to pharmaceutical substances derived from biologicalsources, and increasingly, it is synonymous with 'newer'pharmaceutical substances derived from genetic engineering orhybridoma technology.
This superbly written review of the important areas ofinvestigation in the field, covers drug production, plus thebiochemical and molecular mechanisms of action together with thebiotechnology of major biopharmaceutical types on the market orcurrently under development. There is also additional materialreflecting both the technical advances in the area and detailedinformation on key topics such as the influence of genomics on drugdiscovery.

Autoren/Hrsg.

Walsh, Gary

Inhaltsverzeichnis

Preface.
Chapter 1. Pharmaceuticals, biologies andbiopharmaceuticals.
Chapter 2. The drug development process.
Chapter 3. The drug manufacturing process.
Chapter 4. The cytokines--the interferon family.
Chapter 5. Cytokines: interleukins and tumour necrosisfactor.
Chapter 6. Haemopoietic growth factors.
Chapter 7. Growth factors.
Chapter 8. Hormones of therapeutic interest.
Chapter 9. Blood products and therapeutic enzymes.
Chapter 10. Antibodies, vaccines and adjuvants.
Chapter 11. Nucleic acid therapeutics.
Appendix 1. Biopharmaceuticals thus far approved in the USA orEuropean Union.
Appendix 2. Some Internet addresses relevant to thebiopharmaceutical sector.
Appendix 3. Two selected monographs reproduced from theEuropean Pharmacopoeia with permission from the EuropeanCommission: I. Products of recombinant DNA Technology; II.Interferon a -2 concentrated solution.
Appendix 4. Manufacture of biological medicinal products forhuman use. (Annex 2 from The Rules Governing Medicinal Productsin the European Community, Vol. 4, Good Manufacturing Practices forMedicinal Products).
Index.

Über Autor(innen)

Gary Walsh is a senior lecturer in industrial biochemistry at the University of Limerick, Ireland. He combines industrial experience within the pharmaceutical industry with an extensive teaching and academic research background in pharmaceutical biotechnology. He has published half a dozen highly acclaimed books on various aspects of protein biotechnology. He is on the editorial board of several biopharmaceutical journals and is closely affiliated with the European Association of Pharma Biotechnology, serving as its scientific secretary.