Germfree and Gnotobiotic Animal Models

Background and Applications
1. Auflage 1996
ISBN: 978-0-8493-4008-6
Verlag: Taylor & Francis Inc

Buch, Englisch, 202 Seiten, Format (B × H): 162 mm x 241 mm, Gewicht: 403 g

The germfree animal is reared in the laboratory to be bacteria free; its counterpart, the gnotobiotic animal, is exposed to select microorganisms. The need for such an animal model for use in biomedical studies was first expressed by Pasteur in the late 1800s. Subsequent development of germfree and gnotobiotic animals led to an explosion of studies on the effects of microflora and its components on the physiology and metabolism of the host. Germfree and Gnotobiotic Animal Models brings together the most notable points of early and recent studies and gives reference to the most pertinent literature.

Zielgruppe

Professional

Autoren/Hrsg.

Wostmann, Bernard S.

Fachgebiete

• Medizin | Veterinärmedizin Veterinärmedizin Veterinärmedizin: Labortiere, Tierversuche
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Biomedizin, Medizinische Forschung, Klinische Studien
• Naturwissenschaften Biowissenschaften Mikrobiologie

Inhaltsverzeichnis

Introduction. Early Growth, Body Weight, Reproduction, and Life Span. Anatomy, Morphology, and Function of the Gastrointestinal System. Morphology and Physiology, Endocrinology and Biochemistry. Nutrition. The Chemically Defined Diet. Immunology, Including Radiobiology and Transplantation. Parasitology. Pathology Over the Life Span of the Germfree Rat and the Germfree Mouse. Applications: Past, Present, and Future. Part I. Applications: Past, Present, and Future. Part II. Use of the Gnotobiote in the Study of Disease. Applications: Past, Present, and Future. Part III. The Production of Monoclonal Antibodies and Conclusions. Index.

NTI Copy/Back cover copy

Über Autor(innen)

Bernard S. Wostmann (University of Notre Dame) (Author)