Dendritic Cells: Biophysics, Tumor Microenvironment and Chinese Traditional Medicine

1. Auflage 2015
ISBN: 978-94-017-7403-1
Verlag: Springer Netherlands

Buch, Englisch, 66 Seiten, Format (B × H): 155 mm x 235 mm, Gewicht: 1438 g

Reihe: SpringerBriefs in Biochemistry and Molecular Biology

In this book, the authors discuss the biophysical characteristics of Dendritic cells (DCs) at various differentiation stages and in tumor microenvironments in detail. A type of Chinese traditional herb, which can improve the biophysical and microrheological properties of DCs, is also introduced. DCs are potent and specialized antigen-presenting cells that play a crucial role in initiating and amplifying both the innate and adaptive immune responses. The biophysical and microrheological characteristics of DCs are important for their motility and normal immune function. In tumor microenvironments, the motility and immune functions of DCs are impaired, but the mechanisms are largely unknown. This book offers researchers a comprehensive and deep insight into the biophysical characteristics of DCs and may also help to improve the efficiency of anti-tumor therapy based on DCs.

Zielgruppe

Research

Autoren/Hrsg.

Zeng, Zhu

Chen, Dan

Xu, Xiaofeng

Fachgebiete

• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Onkologie, Krebsforschung
• Naturwissenschaften Physik Angewandte Physik Biophysik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Komplementäre Medizin, Asiatische Medizin (TCM), Heilpraktiker
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie

Inhaltsverzeichnis

Summary.- Introduction.- The measurement protocols of cell biophysical characteristics.- Biophysical characteristics of dendritic cells at different differentiation stages.- Biophysical characteristics of dendritic cells in tumor microenvironment.- Effects of Chinese traditional herbs on dendritic cells.- Future perspectives

Über Autor(innen)

Zhu Zeng is a professor of the Department of Biotechnology, and the vice president of the School of Basic Medical Sciences, Guiyang Medical College. He was awarded as the distinguished young science and technology scholars of Guizhou Province in 2011. Since 2000, his main research interests focused on biophysical characteristics of dendritic cells.  Xiaofeng Xu is a doctor in the department of Laboratory Medicine, Beijing Tongren Hospital, Capital Medical University. Her research interests focused on biophysical characteristics of dendritic cells.  Dan Chen is a lecturer of the Department of Pharmacology, School of Basic Medical Sciences, Tianjin Medical University. Her main research interests focused on the effects of traditional Chinese medicine on tumor biological behaviors.