E-Book, Englisch, Band Volume 77, 334 Seiten, Web PDF
Reihe: Advances in Immunology
Advances in Immunology
1. Auflage 2001
ISBN: 978-0-08-049362-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, Band Volume 77, 334 Seiten, Web PDF
Reihe: Advances in Immunology
ISBN: 978-0-08-049362-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark
Advances in Immunology presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.
Autoren/Hrsg.
Weitere Infos & Material
1;Cover;1
2;Contents;6
3;Contributors;10
4;Chapter 1. The Actin Cytoskeleton, Membrane Lipid Microdomains, and T Cell Signal Transduction;12
4.1;I. Introduction;12
4.2;II. Overview of T Cell Signaling;14
4.3;III. Lipid Rafts;27
4.4;IV. Actin Cytoskeleton;34
4.5;V. Actin Dynamics in Signal TransductionŒGeneral Principles;41
4.6;VI. Conclusion;45
4.7;References;46
5;Chapter 2. Raft Membrane Domains and Immunoreceptor Functions;56
5.1;I. Introduction;56
5.2;II. Lipid Raft Concept: Bridging Biophysics to Biology;57
5.3;III. Immunoreceptor Signaling and Raft Domains;65
5.4;IV. Outlook;90
5.5;References;90
6;Chapter 3. Human Basophils: Mediator Release and Cytokine Production;104
6.1;I. Introduction;104
6.2;II. Basophil Growth and Maturation;105
6.3;III. Cell Surface Markers;105
6.4;IV. Inflammatory Mediators;109
6.5;V. Basophil Activation;112
6.6;VI. Signal Transduction and Pharmacological Control of Secretion;117
6.7;VII. Basophils and Allergic Disease;123
6.8;References;125
7;Chapter 4. Btk and BLNK in B Cell Development;134
7.1;I. Introduction;134
7.2;II. Btk and B Cell Development;135
7.3;III. Activation of Btk;140
7.4;IV. Downstream of Btk;148
7.5;V. BLNK Connects Btk Activity to Downstream Effectors;153
7.6;VI. Conclusion;161
7.7;References;162
8;Chapter 5. Diversity and Regulatory Functions of Mammalian Secretory Phospholipase A2s;174
8.1;I. Introduction;174
8.2;II. Structures and Enzymatic Properties of sPLA2s;175
8.3;III. Expression and Functions of sPLA2s;180
8.4;IV. sPLA2 Receptors;193
8.5;V. Conclusion;194
8.6;References;195
9;Chapter 6. The Antiviral Activity of Antibodies in Vitro and in Vivo;206
9.1;I. Introduction;206
9.2;II. Mechanisms of Neutralization;207
9.3;III. Complement-Mediated Virolysis;236
9.4;IV. Antibody-Mediated Phagocytosis;237
9.5;V. Antibody-Mediated Cytotoxicity;237
9.6;VI. Intracellular Neutralization;238
9.7;VII. Mechanisms of Antibody Protection in Vivo;238
9.8;VIII. Mechanisms of Antiviral Antibody Activity in Established Infection;252
9.9;IX. Observations with Nonviral Pathogens;255
9.10;X. Conclusions;255
9.11;References;259
10;Chapter 7. Mouse Models of Allergic Airway Disease;274
10.1;I. Introduction;274
10.2;II. Conclusion;298
10.3;References;298
11;Chapter 8. Selected Comparison of Immune and Nervous System Development;308
11.1;I. Introduction;308
11.2;II. Major Cellular Components of the Nervous System;308
11.3;III. Embryonic Divisions of the Nervous System;310
11.4;IV. Embryonic Development of the Cerebral Cortex;314
11.5;V. Ventricular Zone Neuroblast Programmed Cell Death;320
11.6;VI. Nonhomologous End-Joining and DNA Rearrangement;324
11.7;VII. Conclusion;327
11.8;References;328
12;Index;334
13;Contents of Recent Volumes;344
