Alouf / Ladant Ph. D / Ladant The Comprehensive Sourcebook of Bacterial Protein Toxins

4. Auflage 2015
ISBN: 978-0-12-800589-7
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 1200 Seiten

The Comprehensive Sourcebook of Bacterial Protein Toxins, Fourth Edition, contains chapters written by internationally known and well-respected specialists. This book contains chapters devoted to individual toxins, as well as chapters that consider the different applications of these toxins. Considerable progress has been made in understanding the structure, function, interaction and trafficking into cells, as well as mechanism of action of toxins. Bacterial toxins are involved in the pathogenesis of many bacteria, some of which are responsible for severe diseases in human and animals, but can also be used as tools in cell biology to dissect cellular processes or used as therapeutic agents. Novel recombinant toxins are already proposed in the treatment of some diseases, as well as new vaccines. Alternatively, certain toxins are also considered as biological weapons or bioterrorism threats. Given the multifaceted aspects of toxin research and the multidisciplinary approaches adopted, toxins are of great interest in many scientific areas from microbiology, virology, cell biology to biochemistry and protein structure. This new edition is written with a multidisciplinary audience in mind and contains 5 new chapters that reflect the latest research in this area. Other chapters have been combined, deleted and fully revised as necessary to deliver relevant and valuable content. - Descriptions of relevant toxins as well as representative toxins of the main bacterial toxin families to allow for a better comparison between them - Focused chapters on toxin applications and common properties or general features of toxins

Joseph E. Alouf is Professor of Microbiology at the Pasteur Institute of Lille. He is former Head of the Department of Bacteriology and Mycology at the Pasteur Institute at Paris and Chairman of its Scientific Council. He served as Secretary General of the French Society of Immunology from 1984-1986 and President of the Federation of the European Microbiological Societies from 1989-1992. His 40-year research work relates to the field of bacterial protein toxins and immunology of infectious diseases. He is also the co-editor of several books.

Autoren/Hrsg.

Alouf, Joseph E.

Ladant Ph. D, Daniel

Ladant, Daniel

Popoff D. V. M., Ph. D

Leseproben

List of Contributors

Klaus Aktories,     Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Universität Freiburg, Freiburg, Germany

Alberto Alape-Girón,     Instituto Clodomiro Picado, Facultad de Microbiología; Departamento de Bioquímica, Escuela de Medicina Universidad de Costa Rica, San José, Costa Rica

Julien Barbier,     Institute of Biology and Technology of Saclay, Gif sur Yvette, France

Joseph T. Barbieri,     Professor Microbiology and Molecular Genetics Medical College of Wisconsin, Milwaukee, WI, USA

Holger Barth,     Institute of Pharmacology and Toxicology, University of Ulm Medical Center, Ulm, Germany

Ajit K. Basak,     Department of Biological Sciences, School of Crystallography, Birkbeck College, Malet Street, London, UK

Roland Benz,     Department of Life Science and Chemistry, Jacobs University Bremen, Bremen, Germany

Kinga Bercsenyi

Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, University College London, London, UK

Molecular NeuroPathobiology Laboratory, Cancer Research UK London Research Institute, London, UK

Jonas Bergan

Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway

Department of Biochemistry, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway

Stefan Bergmann,     Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany

Sergey M. Bezrukov,     Program in Physical Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA

Victoria A. Bjørnestad,     Department of Chemistry, University of Oslo, Oslo, Norway

Patrice Boquet,     Nice University School of Medicine, Nice, France

Laurent Boyer,     INSERM, U1065, C3M, Université de Nice Sophia-Antipolis, Equipe Labellisée Ligue Contre le Cancer, Nice, France

Alejandra Bravo,     Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico

Amy E. Bryant

Infectious Diseases Section, Veterans Affairs Medical Center, Boise, ID, USA

University of Washington School of Medicine, Seattle, WA, USA

Ladislav Bumba,     Laboratory of Molecular Biology of Bacterial Pathogens, Cell and Molecular Microbiology Division, Institute of Microbiology, Academy of Sciences of the Czech Republic, Prague, Czech Republic

Pablo Emiliano Cantón,     Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico

Alexandre Chenal,     Institut Pasteur, CNRS UMR 3528, Unité de Biochimie des Interactions Macromoléculaires, Département de Biologie Structurale et Chimie, Paris, France

Matteo Dal Peraro

Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland

Marcela de Souza Santos,     Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA

Ulrich Dobrindt,     Institute of Hygiene, University of Münster, Münster, Germany

J. Oliver Dolly,     International Centre for Neurotherapeutics, Dublin City University, Dublin, Ireland

J. Daniel Dubreuil,     Department of Pathology and Microbiology, Université de Montréal, Québec, Canada

Alain Filloux,     MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Imperial College London, London, UK

Dara W. Frank,     Professor Microbiology and Molecular Genetics Medical College of Wisconsin, Milwaukee, WI, USA

Marietta Flores-Díaz,     Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica

John D. Fraser,     School of Medical Sciences, University of Auckland and Maurice Wilkins Centre, Auckland, New Zealand

Teresa Frisan,     Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden

Jorge E. Galan,     Department of Microbial Pathogenesis, Yale University School of Medicine, New Haven, CT, USA

Blanca I. García-Gómez,     Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico

Harald Genth,     Institute of Toxicology, Hannover Medical School, Hannover, Germany

Daniel Gillet,     Institute of Biology and Technology of Saclay, Gif sur Yvette, France

Isabel Gómez,     Instituto de Biotecnologia, Universidad Nacional Autónoma de México, Cuernavaca Morelos, Mexico

Per Einar Granum,     Norwegian University of Life Sciences, NMBU—School of Veterinary Science, Department of Food Safety and Infection Biology, Oslo, Norway

Jörg Hacker,     National German Academy of Sciences Leopoldina, Halle/Saale, Germany

Callista B. Harper,     University of Queensland, Queensland Brain Institute, Clem Jones Centre for Ageing Dementia Research, Brisbane, Australia

Julie E. Heggelund,     Department of Chemistry, University of Oslo, Oslo, Norway

Mengfei Ho,     Department of Microbiology, School of Molecular and Cellular Biology, University of Illinois at Urbana-Champaign, Urbana, IL, USA

Eileen M. Hotze,     Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA

Jessica Huyet,     Department of Biological Sciences, School of Crystallography, Birkbeck College, Malet Street, London, UK

Ioan Iacovache,     Laboratory of Experimental Morphology, Institute of Anatomy, University of Bern, Bern, Switzerland

Thomas Jank,     Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Universität Freiburg, Freiburg, Germany

Emmanuel Jover,     EA-7290 Virulence bactérienne précoce, Fédération de Médecine Translationnelle, Université de Strasbourg, Institut de Bactériologie, Strasbourg, France

Ingo Just,     Institute of Toxicology, Hannover Medical School, Hannover, Germany

Anne-Marie Krachler,     Institute of Microbiology and Infection, University of Birmingham, UK

Ute Krengel,     Department of Chemistry, University of Oslo, Oslo, Norway

Daniel Ladant,     Institut Pasteur, CNRS UMR 3528, Unité de Biochimie des Interactions Macromoléculaires, Département de Biologie Structurale et Chimie, Paris, France

Ries J. Langley,     School of Medical Sciences, University of Auckland and Maurice Wilkins Centre, Auckland, New Zealand

Emmanuel Lemichez,     INSERM, U1065, C3M, Université de Nice Sophia-Antipolis, Equipe Labellisée Ligue Contre le Cancer, Nice, France

Stephen...