Andersen Ion Pumps, Part A

1. Auflage 1997
ISBN: 978-0-08-087707-5
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 247 Seiten, Web PDF

Both eukaryotic and prokaryotic cells depend strongly on the function of ion pumps present in their membranes. The term ion pump, synonymous with active ion-transport system, refers to a membrane-associated protein that translocates ions uphill against an electrochemical potential gradient. Primary ion pumps utilize energy derived from chemical reactions or from the absorption of light, while secondary ion pumps derive the energy for uphill movement of one ionic species from the downhill movement of another species. In the present volume, various aspects of ion pump structure, mechanism, and regulation are treated using mostly the ion-transporting ATPases as examples. One chapter has been devoted to a secondary ion pump, the Na+-Ca2+ exchanger, not only because of the vital role played by this transport system in regulation of cardiac contractility, but also because it exemplifies the interesting mechanistic and structural similarities between primary and secondary pumps.

Autoren/Hrsg.

Andersen, J. P.

Inhaltsverzeichnis

1;Cover;1
2;Advances in Molecular and Cell Biology: Ion Pumps;4
3;Copyright Page;5
4;TOC$CONTENTS (Volume 23A);6
5;LIST OF CONTRIBUTORS;10
6;Preface;14
7;Section I;18
7.1;CH$CHAPTER 1. REACTION MECHANISM OF THE SARCOPLASMIC RECTICULUM Ca2+ -ATPASE;18
7.2;CH$CHAPTER 2. THE ATP BINDING SITES OF P-TYPE ION TRANSPORT ATPASES: PROPERTIES, STRUCTURE, CONFORMATIONS, AND MECHANISM OF ENERGY COUPLING ;50
7.3;CH$CHAPTER 3. THE GASTRIC H+-K+-ATPASE ;118
7.4;CH$CHAPTER 4. GENETIC APPROACHES TO STRUCTURE-FUNCTION ANALYSIS IN THE YEAST PLASMA MEMBRANE H+ -ATPASE ;160
7.5;CH$CHAPTER 5. COPPER HOMEOSTASIS BY CPX-TYPE ATPASES: THE NEW SUBCLASS OF HEAVY METAL P-TYPE ATPASES ;184
7.6;CH$CHAPTER 6. ISOSFORM DIVERSITY AND REGULATION OF ORGAN ELLAR-TYPE Ca2+ -TRANSPORT ATPASES ;222
8;Section II;266
8.1;CH$CHAPTER 1. COMPARISON OF ATP-POWERED Ca2+ PUMPS;266
8.2;CH$CHAPTER 2. MOLECULAR MECHANISMS INVOLVED IN THE REGULATIN OF Na-K-ATPase EXPRESSION ;292
8.3;CH$CHAPTER 3. STRUCTURE, MECHANISM, AND REGULATION OF THE CARDIAC SARCOLEMMA Na+-Ca2+ EXCHANGER ;328
8.4;CH$CHAPTER 4. STRUCTURE AND DYNAMICS OF THE F1F0-TYPE ATPASE ;376
8.5;CH$CHAPTER 5. STRUCTURE AND MECHANISM OF F-TYPE ATPASES;398
8.6;CH$CHAPTER 6. STRUCTURE, FUNCTION, AND REGULATION OF THE VACUOLAR (H+)-ATPASES ;420
8.7;CH$CHAPTER 7. ANION TRANSPORT SYSTEMS ;472
9;IDX$Index ;508