Buch, Englisch, Band 677, 473 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 1225 g
Reihe: Methods in Molecular Biology
Methods and Protocols
Buch, Englisch, Band 677, 473 Seiten, Format (B × H): 183 mm x 260 mm, Gewicht: 1225 g
Reihe: Methods in Molecular Biology
ISBN: 978-1-60761-868-3
Verlag: Humana Press
Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results.
Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.
Zielgruppe
Professional/practitioner
Autoren/Hrsg.
Fachgebiete
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
- Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Molekulare Medizin, Zellbiologie
- Naturwissenschaften Biowissenschaften Molekularbiologie
Weitere Infos & Material
Part I: Regulatory Cells
1. Natural and Induced T CD4+CD25+FOXP3+ Regulatory T Cells
Lucienne Chatenoud
2. Polyclonal Expansion of Human CD4+CD25+ Regulatory T Cells
Petra Hoffmann, Ruediger Eder, and Matthias Edinger
3. Methods for In vitro Generation of Human Type 1 Regulatory T (Tr1) Cells
Silvia Gregori, Maria Grazia Roncarolo, and Rosa Bacchetta
4. Ex vivo Generation of Regulatory T-Cells: Characterization and Therapeutic Evaluation in a Model of Chronic Colitis
Fridrik Karlsson, Sherry Jackson, Laura Gray, Songlin Zhang, and Matthew B. Grisham
5. Phenotypic and Functional Characterization of CD8+ T Regulatory Cells
Séverine Ménoret, Carole Guillonneau, Séverine Bezié, Lise Caron, Ignacio Anegon, and Xian-Liang Li
6. Regulatory CD4- CD8- Double Negative T Cells
Edward Y. Kim, Stephen C. Juvet, and Li Zhang
7. Identifying Regulatory B Cells (B10 Cells) that Produce IL-10 in Mice
Takashi Matsushita and Thomas F. Tedder
8. DCs in Immune Tolerance in Steady-State Conditions
Tomohiro Fukaya, Hideaki Takagi, Honami Taya, and Katsuaki Sato
9. Plasmacytoid Dendritic Cells in Tolerance
Eric Gehrie, William Van der Touw, Jonathan S. Bromberg, and Jordi C. Ochando
10. In vitro Generated DC with Tolerogenic Functions: Perspectives for In vivo Cellular Therapy
Cees van Kooten and Kyra A. Gelderman
11. Preparation of Mouse Bone Marrow-Derived Dendritic Cells with Immunoregulatory Properties
Mercedes Segovia, Maria Cristina Cuturi, and Marcelo Hill
12. Myeloid Derived Suppressor Cells (MDSC): Characterization and Expansion in Models of Endotoxemia and Transplantation
Nicolas Van Rompaey and Alain Le Moine
13. Human Regulatory Macrophages
James A. Hutchinson, Paloma Riquelme, Edward K. Geissler, and Fred Fändrich
14. NKT and Tolerance
Julien Diana, Lucie Beaudoin, Anne-Sophie Gautron, and Agnès Lehuen
15. Anti-Inflammatory and Immunosuppressive Functions of Mast Cells
Janet Kalesnikoff and Stephen J. Galli
16. A Mesenchymal Stem Cell Potency Assay
Joy Jiao, Jack M. Milwid, Martin L. Yarmush,
