Targeted Nanotechnology

Enhancing the Efficacy of Natural Anticancer Drug Therapies
1. Auflage 2025
ISBN: 978-1-041-00758-6
Verlag: CRC Press

Buch, Englisch, 592 Seiten, Format (B × H): 210 mm x 280 mm

This book examines the role of nanotechnology in advancing cancer treatment, focusing on phytochemicals derived from natural sources and their therapeutic delivery through nanotechnology. The initial chapters provide an overview of cellular and molecular mechanisms of cancer and present both passive and active targeting strategies to enhance the effectiveness of phytochemical-loaded nanosystems. The chapters also explore the nano-delivery systems tailored for potent anticancer agents such as camptothecin, berberine, paclitaxel, and many more. These molecules improve the bioavailability, stability, and efficacy of these bioactive compounds, addressing the latest innovations for agents like hesperidin, thymoquinone, epigallocatechin gallate, quercetin, and curcumin. The book also investigates the co-delivery of natural and conventional anticancer drugs, exploring potential synergies in cancer therapy. In addition, the chapters focus on nano-delivery systems for essential oils, carotenoids, and phytomolecules targeting drug-resistant cancer cells, and the role of natural compounds in cancer prevention.  Key Features:

- Provides foundational insights into the cellular and molecular mechanisms of cancer

- Explores innovative nano-delivery systems for natural anti-cancer agents from phytoconstituents

- Discusses passive and active targeting strategies for phytochemical-loaded nanosystems

- Highlights the therapeutic potential of nano-formulations for various natural compounds

- Examines co-delivery of natural and synthetic anticancer drugs for improved efficacy

- This book is useful for researchers and students in oncology, nanotechnology, and pharmaceutical sciences.

Zielgruppe

Postgraduate and Professional Reference

Autoren/Hrsg.

Behera, Anindita

Padhi, Santwana

Fachgebiete

• Technische Wissenschaften Technik Allgemein Nanotechnologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Naturwissenschaften Biowissenschaften Botanik

Inhaltsverzeichnis

Chapter 1: Cancer: Cellular and Molecular Basis. Chapter 2: Emerging phytoconstituents from the natural origin in the battle against cancer: overview of molecular mechanisms. Chapter 3: Passive and active targeting strategies for delivery of phytochemical entrapped nanosystems for cancer. Chapter 4: Use of phytochemical entrapped nanosystems for cancer. Chapter 5: Nano-enabled system for delivery of camptothecin as an anticancer agent. Chapter 6: Nano-enabled systems for the delivery of berberine. Chapter 7: Nano-enabled systems for the delivery of Paclitaxel as anticancer agents. Chapter 8: Anticancer nano-drug delivery cargos of artemisinin. Chapter 9: Nano-enabled systems for the delivery of vinca alkaloids as anticancer agent. Chapter 10: Nano-enabled systems for the delivery of hesperidin as anticancer agents. Chapter 11: Nano-enabled systems for the delivery of thymoquinone as anticancer agents. Chapter 12: Nano-enabled systems for delivery of epigallocatechin gallate as anticancer agents. Chapter 13: Nano-enabled system for delivery of quercetin as anticancer agent. Chapter 14: Nano-enabled systems for the delivery of curcumin as an anticancer agent. Chapter 15: Nano-enabled systems for the delivery of resveratrol as an anticancer agent. Chapter 16: Nano-enabled systems for the delivery of cannabinoids as anticancer agent. Chapter 17: Nano-enabled systems for the delivery of anthracyclines as anticancer agents. Chapter 18: Nano-enabled systems for the delivery of different essential oils as an anticancer agent. Chapter 19: Nano-enabled systems for the delivery of carotenoids as anticancer agents. Chapter 20: Nano-enabled systems for the delivery of Docetaxel as anticancer agents. Chapter 21: Co-delivery of natural drugs with other anticancer drugs entrapping nanodelivery systems for cancer. Chapter 22: Drug delivery systems entrapping natural drugs and derivatives: Recent advancements and future challenges. Chapter 23: Phytomolecules targeting resistant cancer cells through nano-delivery systems. Chapter 24: Prevention is better than cure – the role of phytomolecules in the prevention of cancer development.

Über Autor(innen)

Anindita Behera is associated with Amity Institute of Pharmacy, Amity University, Kolkata, in the Department of Pharmaceutical Chemistry as Professor. She earned her master's degree from Pune University, India, and completed her PhD at Siksha 'O' Anusandhan Deemed to be University. Dr. Behera has developed innovative analytical methods for drug formulations used in AIDS treatment and is currently engaged in green synthesis of nanomaterials targeting various life-threatening diseases. With over 18 years of experience in research and academia, she has published numerous research and review articles in peer-reviewed journals. She has also contributed chapters to books published by major international publishers and has authored two books. Dr. Behera has guided three PhD scholars, sixteen postgraduate students, and forty-five undergraduate students in their research pursuits.

Santwana Padhi serves as Scientific Communication Manager at Publication Practice Counsel, USA. She holds a PhD in Pharmaceutics from Jamia Hamdard University, specializing in cancer nanotherapeutics. Her research focuses on preclinical and clinical investigations of drug-loaded targeted nanosystems designed to enhance solid tumor treatment. Before her doctoral studies, she gained hands-on experience as a Research Assistant at the National Institute of Immunology (NII), honing her skills in formulation science. Following her PhD, she worked as a Medical Science Liaison (MSL) at Biocon, contributing to advancements in oncology and dermatology. Later, she joined the KIIT-Technology Business Incubator as Scientific Officer, where she played a key role in supporting entrepreneurial initiatives among young researchers and securing funding for technology development and commercialization. As a Senior Medical Writer at Reseapro Scientific Services, she has contributed to more than 50 publications, medical communication materials, and regulatory documents. Additionally, she has co-edited one book published by Springer Nature. Dr. Padhi has received numerous accolades, including the Senior Research Fellowship (SRF) from ICMR, Junior Research Fellowship (JRF) from DBT, and the Award of Excellence for Scientific Contribution from Jamia Hamdard University for two consecutive years.