Glial Engineering and Glial Interfaces

Targeting the Role of Astrocytes and Other Glial Cells in Brain Function and Dysfunctions
Erscheinungsjahr 2025
ISBN: 978-3-031-94214-3
Verlag: Springer

Buch, Englisch, 358 Seiten, Format (B × H): 160 mm x 241 mm, Gewicht: 721 g

This book focuses on the most recent tools unveiling the role of glial cells in brain function and dysfunction, especially involving epilepsy, ischemia, and glioma. It introduces this emerging field, herein called Glial Engineering, dealing with the development and application of technologies targeting glial cells, with a special focus on astrocytes. The latest glial cell research with biomaterials, gene modification, bioelectronic devices, and computational methods is highlighted. This is an ideal book for undergraduate and research students in tissue engineering, biomedical engineering, neural engineering, chemistry, biomaterials science, and regenerative medicine as well as researchers in the field of biophysics, neurophysiology, and neuroscience.

Zielgruppe

Research

Autoren/Hrsg.

Benfenati, Valentina

Maiolo, Luca

Fachgebiete

• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Astrocytes: multiscale molecular targets for glial engineering and interfaces.- Aquaporin-4 in Astrocytes and Glial Cells: Structural Insights and Functional Implications.- Studying the Role of Astrocytes in Ischemic Acute Brain Slices.- Astrocytes and Potassium Homeostasis in the Central Nervous System in Physiology and Epilepsy.- Genetic-designed tools to unveil the role of astrocytes in neuronal circuits and animal behavior.- Novel treatment options through light-based neurostimulation.- 3D cell-culture systems to study astrocytic phenotypes: current strategies and future perspectives.- Electro Fluid Dynamic Technologies to Engineer 3D Matrices for Glial Cells in Brain.- The Effects of Matrix Mechanical Properties on Glia Behavior.- Graphene-based materials: preparation and use in neuroscience.- Glial Electrophysiology: Technologies for Extracellular Detection.- Flexible and nanostructured electronics to dialogue with glia.

Über Autor(innen)

Valentina Benfenati, PhD, is  Director of Research with the Institute for Organic Synthesis and Photoreactivity, Department of Chemical Sciences and Materials Technologies, National Research Council, Bologna, Italy

Luca Maiolo, PhD, is Senior Researcher with the Institute for Microelectronics and Microsystems, Department of Physical Sciences and Technologies of Matter, National Research Council, Rome, Italy