Blanco's Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis and Treatment

Erscheinungsjahr 2017
ISBN: 978-0-12-809530-0
Verlag: ACADEMIC PR INC

Buch, Englisch, 252 Seiten, Format (B × H): 155 mm x 231 mm, Gewicht: 567 g

Blanco's Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment.

The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels.

Autoren/Hrsg.

Blanco, Ignacio

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft
• Interdisziplinäres Wissenschaften Wissenschaften Interdisziplinär Neurowissenschaften, Kognitionswissenschaft

Inhaltsverzeichnis

1. Alpha-1 Antitrypsin Deficiency: Introduction and History2. Serpins and Serpinopathies3. Alpha-1 Antitrypsin Biology4. Alpha-1 Antitrypsin Gene, Genetic Heritage, Phenotypes, and Genotypes5. Alpha-1 Antitrypsin Deficiency: Liver Pathophysiology6. Alpha-1 Antitrypsin Deficiency: Lung Pathophysiology7. Genetic Epidemiology8. Laboratory Diagnosis9. Clinical Diagnosis10. Liver Disease Associated With Alpha-1 Antitrypsin Deficiency11. Respiratory Manifestations of the Alpha-1 Antitrypsin Deficiency12. Other Diseases Associated With Alpha-1 Antitrypsin Deficiency13. Clinical Management and Treatment of Lung Disease14. Registries and Patients' Associations15. Current Research and Future Perspectives

Über Autor(innen)

Blanco, Ignacio
Ignacio Blanco is the coordinator of the Spanish Registry of Patients with Alpha-1 antitrypsin Deficiency (REDAAT); evaluator of research projects for the Spanish National Agency for Assessment and Forecasting (ANEP).

He is a retired physician and researcher and has held professorships in both the University of Oviedo and the University of Murcia.

Dr. Blanco was an influencial collaborator in the development of the Proyecto IDDEA for the identification and diagnosis of Alpha-1 Antitrypsin Defieciency (AATD) as well as the national screening program for AATD in COPD patients, based on the determination of the Alpha-1 Antitrypsin (AAT) genotype in the Central Laboratoy of the Spanish AAT Registry (Hospital Vall d'Hebron, Barcelona).

He is a founder and member of the Asturian Respiratory Society (ASTURPAR). He is also a member of the European Respiratory Society (ERS) and member of the Spanish Society of Pneumology and Thoracic Surgery (SEPAR). He hold two patents of invention.