Block Advances in Sulfur Chemistry

1. Auflage 2013
ISBN: 978-1-4832-8499-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 226 Seiten, Web PDF

Advances in Sulfur Chemistry, Volume 1 provides information pertinent to the four key aspects of sulfur chemistry. This book illustrates the great utility of sulfur in organic synthesis as applied to the synthesis of cyclic compounds, most of which serve as intermediates in the total synthesis of natural products. Organized into five chapters, this volume begins with an overview of desulfurization using Raney nickel. This text then highlights the extensive research done on compounds containing both phosphorus and sulfur attached to the same carbon atom, revealing synergism involving these adjacent second row heteroatoms. Other chapters consider the significant class of thiaheterocycles and include a discussion of the chemistry of disulfur. The final chapter deals with the chemistry of metal complexes of thiols, with focus on the chemistry, structure, and chemical modeling of the nitrogenase enzyme system, whereby dinitrogen is ultimately reduced to ammonia. This book is a valuable resource for graduate students, postdoctoral fellows, industrial chemists, and those teaching specialized topics to graduate students.

Autoren/Hrsg.

Block, Eric

Inhaltsverzeichnis

1;Front Cover;1
2;Advances in Sulfur Chemistry;4
3;Copyright Page;5
4;Table of Contents;8
5;Dedication;6
6;INTRODUCTION TO THE SERIES: AN EDITOR'S FOREWORD;10
7;PREFACE;12
8;CHAPTER 1. TOTAL SYNTHESIS MEDIATED BY CYCLIC SULFIDES;14
8.1;I. INTRODUCTION;14
8.2;II. RANEY NICKEL DESULFURIZATION;15
8.3;III. RAMBERG-BÄCKLUND SULFUR EXTRUSION;21
8.4;IV. REDUCTIVE SULFUR REMOVAL IN SYNTHESIS;28
8.5;V. SULFUR AS LATENT FUNCTIONALITY IN TOTAL SYNTHESIS;31
8.6;ACKNOWLEDGMENTS;50
8.7;REFERENCES;51
9;CHAPTER 2. a-PHOSPHORYL-SUBSTITUTED ORGANOSULFUR COMPOUNDS;54
9.1;I. INTRODUCTION;55
9.2;II. a-PHOSPHORYL THIOLS;55
9.3;III. a-PHOSPHORYL SULFIDES;58
9.4;IV. a-PHOSPHORYL SULFOXIDES;86
9.5;V. a-PHOSPHORYL SULFONES;99
9.6;VI. NOTE ADDED IN PROOF;104
9.7;REFERENCES;105
10;CHAPTER 3. BIOLOGICALLY INTERESTING SMALL RING DISULFIDES;110
10.1;I. INTRODUCTION;110
10.2;II. DIATOMIC SULFUR AND 3 - AND 4-MEMBERED RING CYCLIC DISULFIDES;111
10.3;III. 5-MEMBERED CYCLIC DISULFIDES (1,2-DITHIOLANES);124
10.4;IV. 6-MEMBERED CYCLIC DISULFIDES;130
10.5;V. BRIDGED BICYCLIC DISULFIDES;135
10.6;REFERENCES AND NOTES;139
11;CHAPTER 4. METAL-THIOLATE COORDINATION CHEMISTRY: A BIOINORGANIC PERSPECTIVE;146
11.1;I. INTRODUCTION;147
11.2;II. THE THIOLATE GROUP;147
11.3;III. METAL-THIOLATE COORDINATION IN ENZYMES AND PROTEINS;152
11.4;IV. NITROGENASE;182
11.5;V. CONCLUSIONS;196
11.6;REFERENCES;196
12;CHAPTER 5. BIOGRAPHICAL SKETCHES OF THE CONTRIBUTORS;208
12.1;THE EDITOR;208
12.2;THE AUTHORS;209
13;INDEX;212