Boas / Pitris / Ramanujam Handbook of Biomedical Optics

1. Auflage 2011
ISBN: 978-1-4200-9037-6
Verlag: Taylor & Francis
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 831 Seiten

Biomedical optics holds tremendous promise to deliver effective, safe, non- or minimally invasive diagnostics and targeted, customizable therapeutics. Handbook of Biomedical Optics provides an in-depth treatment of the field, including coverage of applications for biomedical research, diagnosis, and therapy. It introduces the theory and fundamentals of each subject, ensuring accessibility to a wide multidisciplinary readership. It also offers a view of the state of the art and discusses advantages and disadvantages of various techniques.

Organized into six sections, this handbook:

- Contains introductory material on optics and the optical properties of tissue

- Describes the various forms of spectroscopy and its applications in medicine and biology, including methods that exploit intrinsic absorption and scattering contrast; dynamic contrast; and fluorescence and Raman contrast mechanisms

- Provides extensive coverage of tomography from the microscopic (optical coherence tomography) to the macroscopic (diffuse optical tomography) to photoacoustic tomography

- Discusses cutting-edge translations to biomedical applications in both basic sciences and clinical studies

- Details molecular imaging and molecular probe development

- Highlights the use of light in disease and injury treatment

The breadth and depth of multidisciplinary knowledge in biomedical optics has been expanding continuously and exponentially, thus underscoring the lack of a single source to serve as a reference and teaching tool for scientists in related fields. Handbook of Biomedical Optics addresses this need, offering the most complete up-to-date overview of the field for researchers and students alike.

Zielgruppe

Researchers in optical sciences, biomedical engineering, and related disciplines; advanced undergraduate and graduate students in biomedical engineering and applied physics.

Autoren/Hrsg.

Boas, David A.

Pitris, Constantinos

Ramanujam, Nimmi

Fachgebiete

• Technische Wissenschaften Technik Allgemein Technische Optik, Lasertechnologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Angewandte Optik
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

Preface
David A. Boas, Constantinos Pitris, Nimmi Ramanujam

I. Background
Geometrical Optics
Ting-Chung Poon
Diffraction Optics
Colin Sheppard
Optics: Basic Physics
Raghuveer Parthasarathy
Light Sources, Detectors, and Irradiation Guidelines
Carlo Amadeo Alonzo, Malte C. Gather, Jeon Woong Kang, Giuliano Scarcelli, Seok-Hyun Yun
Tissue Optical Properties
Alexey N. Bashkatov, Elina A. Genina, Valery V. Tuchin

II. Spectroscopy and Spectral Imaging
Reflectance Spectroscopy
Sasha McGee, Jelena Mirkovic, Michael Feld
Multi/Hyper-Spectral Imaging
Costas Balas, Christos Pappas, George Epitropou
Light Scattering Spectroscopy
Le Qiu, Irving Itzkan, Lev T. Perelman
Broadband Diffuse Optical Spectroscopic Imaging
Bruce J. Tromberg, Albert E. Cerussi, So-Hyun Chung, Wendy Tanamai, Amanda Durkin
Near Infrared Diffuse Correlation Spectroscopy for Assessment of Tissue Blood Flow
Guoqiang Yu, Turgut Durduran, Chao Zhou, Ran Cheng, Arjun G. Yodh
Fluorescence Spectroscopy
Darren Roblyer, Richard A. Schwarz, Rebecca Richards-Kortum
Raman, SERS and FTIR Spectroscopy
Andrew J. Berger

III. Tomographic Imaging
Optical Coherence Tomography: Introduction and Theory
Yu Chen, Evgenia Bousie, Constantinos Pitris, James G. Fujimoto
Functional Optical Coherence Tomography in Preclinical Models
Melissa C. Skala, Yuankai K. Tao, Anjul M. Davis, Joseph A. Izatt
Optical Coherence Tomography: Clinical Applications
Brian D. Goldberg, Melissa J. Suter, Guillermo J. Tearney, Brett E. Bouma
Forward Models of Light Transport in Biological Tissue
Andreas H. Hielscher, Hyun Keol Kim, Alexander K. Klose
Inverse Models of Light Transport
Simon Arridge, Martin Schweiger, John C. Schotland
Laminar Optical Tomography
Sean A. Burgess, Elizabeth M. C. Hillman
Diffuse Optical Tomography using Continuous Wave and Frequency Domain Imaging Systems
Subhadra Srinivasan, Scott C. Davis, Colin M. Carpenter
Diffuse Optical Tomography: Time Domain
Juliette Selb, Adam Gibson
Photoacoustic Tomography and Ultrasound-Modulated Optical Tomography
Changhui Li, Chulhong Kim, Lihong V. Wang
Optical and Photoacoustic Molecular Tomography of Small Animals
Vasilis Ntziachristos

IV. Microscopic Imaging
Assesing Microscopic Structural Features Using Fourier-Domain Low Coherence Interferometry
Robert N. Graf, Francisco E. Robles, Adam Wax
Phase Imaging Microscopy: Beyond Darkfield, Phase and Differential Interference Contrast Microscopy
Chrysanthe Preza, Sharon V. King, Nicoleta M. Dragomir, Carol J. Cogswell
Confocal Microscopy
William C. Warger II, Charles A. DiMarzio, Milind Rajadhyaksha
Fluorescence Microscopy with Structured Excitation Illumination
Alexander Brunner, Gerrit Best, Roman Amberger, Paul Lemmer, Thomas Ach, Stefan Dithmar, Rainer Heintzmann, Christoph Cremer
Nonlinear Optical Microscopy for Biology and Medicine
Daekeun Kim, Heejin Choi, Jae Won Cha, Peter T. C. So
Fluorescence Lifetime Imaging Microscopy, Endoscopy and Tomography
James McGinty, Clifford Talbot, Dylan Owen, David Grant, Sunil Kumar, Neil Galletly, Bebhinn Treanor, Gordon Kennedy, Peter M. P. Lanigan, Ian Munro, Daniel S. Elson, Anthony Magee, Dan Davis, Gordon Stamp, Mark Neil, Christopher Dunsby, Paul W. M. French
Application of Digital Holographic Microscopy in Biomedicine
Christian Depeursinge, Pierre Marquet, Nicolas Pavillon
Polarized Light Imaging of Biological Tissues
Steven L. Jacques

V. Molecular Probe Development
Molecular Reporter Systems for Optical Imaging
Walter J. Akers, Samuel Achilefu
Nanoparticles for Targeted Therapeutics and Diagnostics
Timothy Larson, Kort Travis, Pratixa Joshi, Konstantin Sokolov
Plasmonic Nanoprobes for Biomolecular Diagnostics of DNA Targets
Tuan Vo-Dinh, Hsin-Neng Wang

VI. Phototherapy
Photodynamic Therapy
Jarod C. Finlay, Keith Cengel, Theresa M. Busch, Timothy C. Zhu
Low Level Laser and Light Therapy
Ying-Ying Huang, Aaron C-H Chen, Michael R. Hamblin

Über Autor(innen)

Dr. David A. Boas is an Associate Professor at the Harvard Medical School and Associate Physicist at Massachusetts General Hospital in Boston, Massachusetts. He received his Bachelors Degree in Physics from Rensselaer Polytechnic Institute, Troy NY in 1991 and his Doctorate from the University of Pennsylvania, Philadelphia, PA, also in Physics. His research interests include the following: photon migration in highly scattering media with emphasis on diffuse optical tomography, clinical applications of diffuse optical tomography in brain and breast radiology and fundamental studies of brain function and stroke using diffuse optical tomography and optical microscopy. Dr. Boas has been an Associate Editor of Optics Express and Guest Editor of Medical Physics and Journal of Biomedical Optics. He is a member of SPIE and the Optical Society of America (OSA), and has served as Conference Program Chair for various OSA topical meetings.
Dr. Constantinos Pitris is an Assistant Professor in the faculty of Electrical and Computer Engineering at the University of Cyprus. He completed his studies at the University of Texas at Austin (BS Honors in Electrical Engineering, 1993, MS in Electrical Engineering, 1995), Massachusetts Institute of Technology (Ph.D. in Electrical and Medical Engineering, 2000), and Harvard Medical School (MO Magna Cum Laude in Medicine, 2002). He has worked as a research assistant at the University of Texas and Massachusetts Institute of Technology and as a postdoctoral associate at the Wellman Laboratories of Photomedicine of the Massachusetts General Hospital and Harvard Medical School. His main research interests cover the areas of optics and biomedical imaging. The goal of this research is the introduction of new technologies in clinical applications for the improvement of diagnostic and therapeutic options. He is an active member of the OSA and a reviewer for Optics Letters, Applied Optics and Biomedical Optics.
Dr. Nimmi Ramanujam is an Associate Professor of Biomedical Engineering at Duke University. Dr. Ramanujam earned her Ph.D. in Biomedical Engineering from the University of Texas, Austin in 1995 and trained as an NIH postdoctoral fellow at the University of Pennsylvania from 1996-2000. Prior to her tenure at Duke, she was an assistant professor in the Department of Biomedical Engineering at the University of Wisconsin, Madison from 2000-2005. Dr. Ramanujam's interests in the field of biophotonics are centered on research and technology development for applications to cancer. She is developing novel quantitative optical sensing and imaging tools for translational applications in cancer research. She has been leading a multidisciplinary effort to translate these technologies into pre-clinical models and cancer patients. Dr. Ramanujam is a fellow of the OSA and was invited to be a panel member for the Department of Defense (DOD) Breast Cancer Research Program (BCRP) Integration Panel. She has received several awards for her work in cancer research and technology development, including Era of Hope Scholar awards from the DOD and a Global Indus Technovator award from MIT.