Chadwick / Goode Mast Cells and Basophils

Development, Activation and Roles in Allergic / Autoimmune Disease
1. Auflage 2006
ISBN: 978-0-470-03051-6
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 274 Seiten, E-Book

Reihe: Novartis Foundation Symposia

The book presents recent advances relating to the factors and mechanisms that regulate the growth, differentiation and function of mast cells and basophils; discussion of new technologies used to study these cells, and integration of the basic scientific findings in the context of therapeutic possibilities for the treatment of diseases such as allergic inflammation and autoimmune disease which are mediated, in part, by these granulocytes.

Autoren/Hrsg.

Chadwick, Derek J.

Goode, Jamie A.

Inhaltsverzeichnis

Symposium on Mast cells and basophils: development, activationand roles in allergic/autoimmune disease, held at the NovartisFoundation, London, 16-18 November 2004
Editors: Derek J. Chadwick (Organizer) and Jamie Goode
This symposium was based on a proposal made by Santa JeremyOno.
Santa Jeremy Ono: Chair's Introduction.
Yukihiko Kitamura MITF and SgIGSF: an essentialtranscription factor and its target adhesion molecule fordevelopment and survival of mast cells
Discussion.
Paul J. Bryce, Mendy L. Miller, Ichiro Miyajima, Mindy Tsai,Stephen J. Galli and Hans C. Oettgen: Immunesensitization in the skin is enhanced by antigen-independenteffects of IgE on mast cells
Discussion.
Yasuko Furumoto, Gregorio Gomez, Claudia Gonzalez-Espinosa,Martina Kovarova, Sandra Odom, John J. Ryan and JuanRivera: The role of Src family kinases in mast cell effectorfunction
Discussion.
Richard L. Stevens, Nasa Morokawa, Jing Wang andSteven A. Krilis: RasGRP4 in mast-cell signalling anddisease susceptibility
Discussion.
J. Abramson, E. A. Barbu and I. Pecht: Regulationof mast cell secretory response to the type I Fce receptor:inhibitory elements and desensitization
Discussion.
General discussion I.
Toshiaki Kawakami, Jiro Kitaura, Wenbin Xiao and YukoKawakami: IgE regulation of mast cell survival andfunction
Discussion.
See-Ying Tam, Janet Kalesnikoff, Susumu Nakae, Mindy Tsaiand Stephen J. Galli: RabGEF1, a negative regulator of Rassignalling, mast cell activation and skin inflammation
Discussion.
Masako Toda, Takao Nakamura, Masaharu Ohbayashi, YoshifumiIkeda, Maria Dawson, Ricardo Micheler Richardson, Andrew Alban,Benjamin Leed, Dai Miyazaki and Santa Jeremy Ono: Roleof CC chemokines and their receptors in multiple aspects of mastcell biology: comparative protein profiling of FceRI- and/orCCR1-engaged mast cells using protein chip technology
Discussion.
General discussion II.
Shigeo Koyasu, Akiko Minowa, Yasuo Terauchi, TakashiKadowaki and Satoshi Matsuda: The role ofphosphoinositide-3-kinase in mast cell homing to thegastrointestinal tract
Discussion.
K. Frank Austen: The mast cell and the cysteinylleukotrienes
Discussion.
Silvia Monticelli, K. Mark Ansel, Dong U. Lee andAnjana Rao: Regulation of gene expression in mast cells:micro-RNA expression and chromatin structural analysis of cytokinegenes
Discussion.
Cellina Cohen-Saidon and Ehud Razin: Theinvolvement of Bcl-2 in mast cell apoptosis
Discussion.
General discussion III.
P. A. Nigrovic and D. M. Lee: Mast cells inautoantibody responses and arthritis
Discussion.
Greg D. Gregory, Allison Bickford, Michaela Robbie-Ryan,Mindy Tanzola and Melissa A. Brown: MASTering the immuneresponse: mast cells in autoimmunity
Discussion.
Dean D. Metcalfe: Mastocytosis
Discussion.
Index of Contributors.
Subject Index.