Chavda / Desai | Data Science in Pharmaceutical Development | Buch | 978-1-394-28735-2 | www.sack.de

Buch, Englisch, 416 Seiten

Chavda / Desai

Data Science in Pharmaceutical Development


1. Auflage 2025
ISBN: 978-1-394-28735-2
Verlag: Wiley

Buch, Englisch, 416 Seiten

ISBN: 978-1-394-28735-2
Verlag: Wiley


This book is an indispensable guide for anyone looking to understand how AI, machine learning, and data science are revolutionizing drug discovery, development, and delivery, offering practical insights and addressing crucial real-world applications and considerations.

Data Science in Pharmaceutical Development offers a comprehensive and forward-looking exploration of how artificial intelligence, machine learning, and data science are reshaping the pharmaceutical landscape. From the earliest stages of drug discovery to advanced delivery systems and post-market surveillance, this volume bridges the gap between innovation and real-world application. Practical examples and case studies bring to life the transformative potential of AI-powered tools in accelerating research, enhancing patient outcomes, and improving efficiency throughout the pharmaceutical product lifecycle.

Designed for researchers, industry professionals, and students alike, this book not only showcases cutting-edge technologies but also addresses the ethical, legal, and regulatory considerations critical to their implementation. Whether you’re navigating the complexities of clinical trials, optimizing supply chains, or seeking to understand the implications of smart drug delivery systems, this book is an indispensable guide to the future of medicine and healthcare innovation.

Readers will find the book: - Explores the role of AI, machine learning, and data science across the entire pharmaceutical pipeline—from drug discovery and clinical trials to smart drug delivery systems;
- Rich with real-world case studies and practical examples, connecting theory to implementation in modern pharmaceutical research and development;
- Introduces advanced topics like predictive modeling, personalized medicine, IoT, pharmacovigilance, and nanotechnology-enabled drug delivery;
- Highlights emerging trends, ethical considerations, and the regulatory framework surrounding AI in healthcare.

Audience

Research scholars, pharmacy students, pharmaceutical process engineers, and pharmacy professionals in the pharmaceutical and biopharmaceutical industry who are working in drug discovery, chemical biology, computational chemistry, medicinal chemistry, and bioinformatics.

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Weitere Infos & Material


Foreword xix

Preface xxi

Part 1: Fundamentals of Data Science in Pharmaceuticals 1

1 Introduction to AI in Medicine and Drug Delivery 3
Dixa A. Vaghela, Pankti C. Balar and Vivek P. Chavda

1.1 Introduction 3

1.2 Applications of AI in Medicine 4

1.2.1 AI in Drug Discovery 5

1.2.1.1 Target Identification 5

1.2.1.2 Compound Selection 5

1.2.1.3 Predictive Modeling in Drug Discovery 5

1.2.2 Personalized Medicine 6

1.2.2.1 Tailoring Treatments 6

1.2.2.2 Genetic and Lifestyle Consideration 6

1.2.3 Advanced AI Techniques in Medicine 7

1.2.3.1 Medical Imaging and Diagnostic 7

1.2.3.2 Patient Monitoring and Remote Care 7

1.2.3.3 Surgical Assistance and Robotics 7

1.3 AI in Drug Delivery Systems 8

1.3.1 Smart Drug Delivery Networks 8

1.3.2 Nanotechnology-Based Drug Delivery 9

1.4 Future Trends and Ethical Considerations 10

1.5 Conclusion 12

References 14

2 Data Visualization in Pharmaceutical Development 19
Gagandeep Kaur, Benu Chaudhary, Vikas Sharma, Parul Sood and Rupesh K. Gautam

2.1 Introduction 20

2.2 Digitalization of a Continuous Process Manufacturing for Formulated Products 21

2.2.1 Data Visualization and Cloud Integration 21

2.3 Clinical Trial Data Visualization 22

2.4 Decision Making in Product Portfolios of Pharmaceutical Research and Development—Managing Streams of Innovation in Highly Regulated Markets 24

2.5 Genomic Data Visualization 24

2.5.1 Opportunities and Challenges 25

2.6 Real-World Evidence (RWE) Research 29

2.7 Pharmacokinetic/Pharmacodynamic (PK/PD) Indices 31

2.8 Supply Chain Visualization 32

2.9 Designing Medical Data Visualizations 32

2.10 Pharmacovigilance: Data Visualization 33

2.11 Health Econometric: Data Visualization 35

2.12 Explainable Artificial Intelligence: Visualizing 37

2.13 Conclusion 39

References 39

3 Data Science and AI for Transforming R&D 47
Parul Sood, Gagandeep Kaur, Jatin Kumar, Narinderpal Kaur, Nitin Jangra and Rupesh K. Gautam

3.1 Introduction 48

3.2 Artificial Intelligence and Machine Learning 49

3.3 Data Science and AI for Transforming R&D 50

3.4 Machine Learning and AI Approaches in Drug Discovery 51

3.4.1 Target Selection and Validation 51

3.4.2 Drug Design 52

3.4.3 ADMET Modeling 52

3.5 Methods for Improving Existing Approaches in R&D 53

3.5.1 Deep Learning for Protein Structure Prediction and Drug Repurposing 55

3.5.2 AI in Advancing Pharmaceutical Product Development 56

3.5.3 Machine Learning/AI for Developing Predictive Biomarkers 57

3.5.4 AI in Product Cost 57

3.5.5 AI Emergence in Nanomedicine 58

3.5.6 AI/ML for Precision Medicine 58

3.5.7 AI/ML in Quality Control and Quality Assurance 59

3.5.8 AI/ML-Assisted Tool for Clinical Trial Oversight 60

3.5.9 AI in Finding the Hit or Lead 61

3.6 Conclusion 61

References 62

Part 2: Applications of Data Science in Pharmaceutical Development 67

4 Applications of Medical IoT and Smart Sensor Paradigm for Handling Patients 69
Keshava Jetha, Krupa Vyas, Jalpan Shah, Dhvani Trivedi and Ritul Patel

4.1 Introduction to Medical IoT and Smart Sensors 70

4.2 IoT and Smart Sensor in Chronic Disease Management 71

4.3 IoT and Smart Sensors in Post-Operative Monitoring 76

4.4 Applications of Medical IoT and Smart Sensor 78

4.5 Remote Patient Monitoring 83

4.6 Enhancing Patient Safety and Ethical Perspective 87

4.7 Future Directions and Challenges 88

4.8 Conclusion 91

References 92

5 Predictive Models for Drug Development Using Expert Systems 103
Nirmal Joshi, Deepak Chandra Joshi, Suraj Koranga, Kajal Gurow and Mayuri Bapu Chavan

5.1 Introduction to Predictive Modeling in Drug Development 104

5.1.1 Overview of the Drug Development Process 104

5.1.2 Role of Predictive Modeling in Drug Discovery and Development 105

5.1.3 Introduction to Expert Systems and Their Applications in Pharmaceutical Research 105

5.1.4 Importance of Predictive Models in Accelerating Drug Development Timelines 107

5.2 Fundamentals of Expert Systems 107

5.2.1 Definition and Characteristics of Expert Systems 108

5.2.2 Components of Expert Systems: Knowledge Base, Inference Engine, User Interface 109

5.2.3 Types of Expert Systems: Rule-Based, Fuzzy Logic, Bayesian Networks, etc. 110

5.2.4 Advantages and Limitations of Expert Systems in Drug Development 112

5.2.5 Advantages of Expert Systems in Drug Development 112

5.2.6 Limitations of Expert Systems in Drug Development 112

5.3 Data Collection and Pre-Processing for Predictive Modeling 113

5.3.1 Sources of Data in Drug Development: Clinical Trials, Pre-Clinical Studies, Literature, Databases, etc. 113

5.3.2 Data Pre-Processing Techniques: Data Cleaning Feature Selection, Normalization, etc. 114

5.3.3 Challenges in Data Collection and Pre-Processing for Predictive Modeling in Drug Development 114

5.4 Building Rule-Based Expert Systems for Drug Development 117

5.4.1 Principles of Rule-Based Systems 117

5.4.2 Knowledge Acquisition: Expert Interviews, Literature Review, and Data Analysis 118

5.4.3 Rule Generation and Representation 119

5.4.4 Case Studies Illustrating the Development of Rule-Based Expert Systems for Drug Discovery and Development 121

5.5 Applications of Fuzzy Logic in Predictive Modeling 121

5.5.1 Introduction to Fuzzy Logic and Fuzzy Sets 121

5.5.2 Fuzzy Inference Systems for Drug Development 123

5.5.3 Case Studies Demonstrating the Application of Fuzzy Logic in Predicting Pharmacokinetic Parameters, Toxicity, etc. 125

5.6 Bayesian Networks in Drug Development 126

5.6.1 Basics of Bayesian Networks 126

5.6.1.1 Applications of Bayesian Networks in Drug Development 126

5.6.1.2 Advantages of Utilizing BNs in Pharmaceutical Research 127

5.6.2 Bayesian Networks for Predicting Drug-Target Interactions, Drug Efficacy, Adverse Effects, etc. 127

5.6.3 Challenges and Opportunities in Using Bayesian Networks for Predictive Modeling in Drug Development 129

5.7 Integration of Predictive Models in Drug Development Workflow 130

5.7.1 Incorporating Predictive Models into Decision-Making Processes 130

5.7.2 Challenges in Integrating Predictive Models with Experimental Data 132

5.7.3 Real-World Examples of Successful Integration of Predictive Models in Drug Development Pipelines 132

5.8 Validation and Evaluation of Predictive Models 133

5.8.1 Importance of Model Validation and Evaluation 133

5.8.2 Validation Techniques: Cross-Validation, Bootstrapping, External Validation, etc. 134

5.8.2.1 Validation Techniques 134

5.8.3 Performance Metrics for Evaluating Predictive Models in Drug Development 134

5.8.4 Considerations for Selecting Appropriate Validation Methods Based on the Type of Predictive Model 135

5.9 Future Perspectives and Emerging Trends 136

5.9.1 Advances in Predictive Modeling Techniques for Drug Development 136

5.9.2 Role of Artificial Intelligence and Machine Learning in Enhancing Predictive Modeling Capabilities 136

5.9.3 Challenges and Opportunities in the Future of Predictive Modeling in Pharmaceutical Research 137

5.10 Conclusion 138

5.10.1 Drug Development 138

5.10.1.1 Improved Drug Discovery 139

5.10.1.2 Personalized Medicine 139

5.10.1.3 Integration of Multi-Omics Data 139

5.10.1.4 Enhanced AI Algorithms 139

5.10.1.5 Big Data Analytics 139

5.10.1.6 Collaborative Research Efforts 139

References 139

6 Adverse Impact of Human Data Science in Pharmacovigilance (HDS-PV) and Their Potential Applications 151
B. Prabadevi, M. Pradeepa, S. Sudhagara Rajan and S. Kumaraperumal

6.1 Introduction 152

6.2 Pharmacovigilance 153

6.2.1 Introduction to Pharmacovigilance 153

6.2.2 Phases in Pharmacovigilance 154

6.3 Human Data Science in Pharmacovigilance 157

6.3.1 Human Data Science 157

6.3.2 Data for Human Data Science in Pharmacovigilance (hds-pv) 157

6.3.3 Medical Data for Pharmacovigilance 158

6.3.4 Techniques in Human Data Science 162

6.3.4.1 Data Mining 162

6.3.4.2 Disproportionality 163

6.3.4.3 Change-Point Analysis (CPA) 163

6.3.4.4 Geographical Information Systems (GIS) 164

6.3.4.5 Natural Language Processing and Its Application 164

6.3.4.6 Artificial Intelligence Methodologies 165

6.3.4.7 Data Visualization 166

6.4 Challenges in the Amalgamation of Human Data Science and Pharmacovigilance 169

6.4.1 Potential Risks in Pharmacovigilance 169

6.4.2 Data Challenges in HDS-PV 170

6.4.3 Various Errors in the Process 172

6.4.4 Legal Issues and Concerns 172

6.4.5 Other Challenges 173

6.5 Future Research Prospects 173

6.5.1 Federated Learning for Pharmacovigilance 173

6.5.2 Explainable AI to Avoid Transparency Issues 174

6.5.3 Blockchain for Enhanced Security 174

6.5.4 6G and Beyond for Pharmacovigilance 175

6.6 Conclusion 175

References 176

7 Data Science for Product Lifecycle Management 181
Bhagyashree N. Singh, Shivani Gandhi and Nisha Parikh

Abbreviation 182

7.1 Introduction 182

7.1.1 The Beginner’s Guide to Product Lifecycle Management 183

7.1.2 Alliteration Techniques in Data Science of Product Lifecycle Management 185

7.2 Role of Data Science in Preclinical Trial Studies for Product Lifecycle Management 187

7.2.1 Clinical Trial Organizations Significantly Improving Pharmaceutical Manufacturing 190

7.2.1.1 Enhancing Efficiency with the Internet of Things (IoT) in Pharma 190

7.2.1.2 Integrating the Internet of Things in Pharmaceutical Manufacturing 191

7.2.1.3 Techniques for Integrating the Internet of Things in Waste Management Systems 191

7.3 Exploring Data Science Applications in Active Ingredient Management 191

7.3.1 Data Science: A Catalyst for Advancement in Protein Design 193

7.3.1.1 Assessing Risks of AI-Designed Protein 193

7.3.2 Role of Artificial Intelligence/Machine Learning in Modern Pharmacology 195

7.4 Machine Learning Algorithms for Toxicity Prediction 196

7.4.1 Machine Learning Tools Used in Drug Development 199

7.5 Redefining R&D Efficiency in Pharma through Data Science 202

7.6 Intersection of Data Science and Pharmacovigilance 202

7.6.1 The Challenges of Data Science in Pharmacovigilance 203

7.7 Ways to Enhance Product Lifecycle Management Stability in Data Science 204

7.7.1 Data Science Improving Quality Management System 205

7.7.2 Impactful Data Science Trends in the Pharmaceutical Industry 205

7.7.3 Utilization of Data Science in Pharma Regulations 206

7.8 Optimizing Product Lifecycle with Data Science 207

7.9 Conclusion 208

References 209

8 Data Science for Quality Management 217
Dixa A. Vaghela, Amit Z. Chaudhari, Pankti C. Balar, Anup Kumar, Hetvi Solanki and Vivek P. Chavda

8.1 Introduction 218

8.2 Literature Review 220

8.2.1 Historical Context of Quality Management 220

8.2.2 Evolution of Data Science 221

8.2.3 Integration of Data Science in Quality Management 223

8.2.3.1 Data Quality Management 223

8.2.3.2 Process Monitoring and Control 224

8.2.3.3 Root Cause Analysis 224

8.2.3.4 Optimization and Design of Experiments 224

8.2.4 Key Theories and Frameworks 225

8.2.4.1 Total Data Quality Management (TDQM) 225

8.2.4.2 Six Sigma 225

8.3 Data Quality Dimension 226

8.3.1 Definition of Data Quality Dimensions 226

8.3.2 Key Dimensions of Data Quality 227

8.3.2.1 Timeliness 227

8.3.3 Measuring Data Quality 227

8.4 Data Quality Management 228

8.4.1 Overview of Data Quality Frameworks 228

8.4.2 Components of a Data Quality Framework 229

8.4.2.1 Data Profiling and Assessment 230

8.4.2.2 Data Governance and Stewardship 231

8.4.2.3 Data Cleansing and Enrichment 231

8.4.2.4 Continuous Monitoring and Improvement 232

8.4.3 Common Data Quality Frameworks 233

8.4.3.1 Dama Dmbok 233

8.4.3.2 Cobit 234

8.4.3.3 Itil 235

8.5 Challenges and Barriers 236

8.5.1 Common Challenges in Data Quality Management 236

8.5.1.1 Data Accuracy and Integrity 236

8.5.1.2 Completeness of Data 236

8.5.1.3 Data Consistency Across Platforms 237

8.5.1.4 Timeliness of Data 237

8.5.1.5 Relevance to Quality Management Goals 237

8.5.2 Barriers to Implementing Data Science in Quality Management 237

8.5.2.1 Technological Barriers 237

8.5.2.2 Organizational Resistance to Change 239

8.5.2.3 Skills Gap in the Workforce 239

8.5.2.4 Data Privacy and Security Concerns 239

8.5.2.5 Financial Constraints 239

8.5.3 Strategies to Overcome Challenges 241

8.5.3.1 Investing in Scalable Technological Infrastructure 241

8.5.3.2 Promoting Organizational Change and Cultivating a Data-Driven Culture 242

8.5.3.3 Addressing the Skills Gap and Enhancing Workforce Readiness 242

8.5.3.4 Ensuring Data Privacy and Security Compliance 243

8.5.3.5 Implementing Cost-Effective Solutions for SMEs 244

8.6 Future Directions 245

8.6.1 Emerging Trends in Data Science and Quality Management 245

8.6.1.1 Big Data Analytics 245

8.6.1.2 Predictive and Prescriptive Analytics 245

8.6.1.3 Cloud-Based Quality Management Systems (qms) 246

8.6.1.4 Advanced Data Visualization 246

8.6.2 The Role of Artificial Intelligence 246

8.6.2.1 AI-Powered Quality Control 246

8.6.2.2 Predictive Maintenance with AI 247

8.6.2.3 AI in Customer Feedback Analysis 247

8.6.2.4 AI for Continuous Improvement 247

8.7 Conclusion 247

References 249

9 Data Science for Validation 259
Shiwali Sharma, Narinderpal Kaur, Gagandeep Kaur and Parul Sood

9.1 Introduction 260

9.1.1 Overview of Validation in Data Science 261

9.1.2 Definition of Validation 262

9.1.3 Types of Validation 262

9.1.4 Accepting and Relating the Types of Validation 262

9.2 Importance of Validation 263

9.2.1 Why Validation is Crucial for Data Science Projects 263

9.2.2 Risks and Consequences of Neglecting Validation 263

9.2.2.1 Inaccurate Predictions 264

9.2.3 Addressing the Risks — Strategies for Effective Validation 264

9.2.4 Validation as an Iterative Process 265

9.3 Data Validation 266

9.3.1 Methods for Validating Data Quality and Integrity 266

9.3.1.1 Addressing Common Issues in Data Validation 267

9.3.2 Model Validation 267

9.3.2.1 Techniques for Validating Predictive Models 267

9.3.3 Process Validation 268

9.3.3.1 Importance of Validating Data Processing Pipelines 268

9.4 Validation Techniques and Tools 268

9.4.1 Statistical Methods 268

9.4.2 Machine Learning Techniques 270

9.4.3 Validation Tools 270

9.5 Challenges in Data Science Validation 271

9.5.1 Data Challenges 271

9.5.2 Model Challenges 272

9.5.3 Addressing Data and Model Challenges 273

9.6 Case Studies 274

9.6.1 Case Study: Manufacturing Predictive Maintenance 274

9.6.2 Case Study: Fraud Detection in Financial Transactions 275

9.7 Future Trends in Data Science Validation 276

9.7.1 Emerging Trends and Technologies 276

9.7.2 Role of AI and Automation in Improving Validation Processes 278

9.8 Conclusion 279

References 279

Part 3: Advanced Topics and Future Prospects 285

10 Data Science and Classification of Medical Data for Pharmacovigilance 287
Rutvi Vaidya, Bhavin Vyas, Shrikant Joshi, Sonia Singh, Dhwani Desai and Preeti Bhatt

10.1 Introduction to Data Science 287

10.2 Data Processing 289

10.2.1 Data Gathering 289

10.2.2 Data Cleaning 289

10.2.3 Data Integration 289

10.2.4 Data Transformation 290

10.2.5 Data Storage 290

10.2.6 Data Analysis 290

10.2.7 Data Visualization 290

10.3 Types of Healthcare Data 291

10.3.1 Clinical Data 291

10.3.2 Administrative Data 292

10.3.3 Financial Data 292

10.3.4 Patient-Generated Data (PGD) 293

10.3.5 Public Health Data 293

10.3.6 Claims Data 293

10.3.7 Data from Wearable Devices 293

10.4 Classification of Medical Data Using Data Science 294

10.4.1 The Importance of Medical Data Classification 294

10.4.2 Challenges in Medical Data Classification 294

10.4.3 Data Mining Techniques for Medical Data Classification 295

10.4.4 Machine Learning Approaches 296

10.4.5 Case Studies in Medical Data Classification 297

10.4.6 Future Directions in Medical Data Classification 297

10.5 Role and Significance of Data Science in Pharmacovigilance 298

10.5.1 What is Data Science? 298

10.5.2 What is Pharmacovigilance? 298

10.5.3 Search Strategy 299

10.5.4 Various Applications of Data Science 299

10.6 Data Processing Algorithms — AI, ML, and dl 300

10.6.1 AI and ML Algorithms for Pharmacovigilance 300

10.6.2 Challenges and Considerations in Adopting AI/ML for Pharmacovigilance 300

10.6.3 The Future of Pharmacovigilance with AI/ML 301

10.6.4 Advancements in Deep Learning for Pharmacovigilance 301

10.6.5 Challenges and Limitations for Deep Learning in Pharmacovigilance 302

10.7 Predictive Models for Adverse Drug Reaction Detection 303

10.7.1 Introduction to Pharmacovigilance and Its Importance in Healthcare Analytics 303

10.7.2 Predictive Models in Pharmacovigilance: From Logistic Regression to Neural Networks 304

10.7.3 Challenges and Future Directions in Predictive Modeling for Pharmacovigilance 305

10.7.4 Key Insights and Perspectives of Predictive Model in Pharmacovigilance 306

10.8 Application in Regulatory Attainment 306

10.9 Availability of Open-Source Tools 307

10.9.1 Introduction 307

10.9.2 Data Collection and Management 308

10.9.3 Data Integration and Interoperability 315

10.9.4 Data Repositories and Ontologies 320

10.10 Future Prospects and Ethical Considerations 328

10.11 Conclusion 329

References 330

11 Data Science for Analytical Development and Quality Control 337
Kunjan Bodiwala, Rahul Lalwani, Zalak Jain and Anuradha Gajjar

11.1 Introduction 337

11.2 Importance of Analytical Development and Quality Control in Pharmaceutical Industry 340

11.3 Digitalization and Data Science in Pharma 4.0 345

11.4 Data Science Tools for Process Development 347

11.4.1 Process Understanding 347

11.4.2 Product Understanding 348

11.4.3 Key Tools Relevant to Process Development 348

11.4.4 Specific Tools Relevant to the Analytical Development Stage 350

11.5 Role of Data Science in Analytical Development and Quality Control 352

11.5.1 Applications of Data Science in Analytical Laboratories 355

11.5.1.1 Automation and Efficiency 355

11.5.1.2 Sample Preparation and Analysis 355

11.5.1.3 Data Management and Laboratory Information Management Systems (lims) 356

11.5.1.4 Quality Assurance and Monitoring 356

11.5.1.5 Statistical Process Control (SPC) 356

11.5.1.6 Predictive Analytics and Risk Mitigation 356

11.5.1.7 Machine Learning for Method Optimization 357

11.5.1.8 Algorithmic Approaches to Method Development 357

11.5.1.9 Predictive Modeling for Method Validation 358

11.5.1.10 Real-Time Data Visualization 358

11.5.1.11 Interactive Dashboards and Key Performance Indicators (KPIs) 358

11.5.1.12 Collaborative Data Sharing 358

11.5.2 Case Studies in Data Science Integration 359

11.6 Applications of Data Science in Quality Control 361

11.6.1 Predictive Models for Drug Development 362

11.6.2 Application of Machine Learning 362

11.6.3 Forecasting Patient Flow and Demand 362

11.6.4 Time Series Analysis and Demand Forecasting 363

11.6.5 Integrating External Factors 363

11.6.6 Real-Time Analysis and Process Verification 363

11.6.7 Implementing Advanced Sensors and IoT 364

11.6.8 Benefits of Real-Time Analysis 364

11.6.9 Statistical Quality Control and Process Monitoring 364

11.6.10 Control Charts and Process Capability Analysis 364

11.6.11 Data Science Enhancements 365

11.6.12 Continued Process Verification (CPV) Using Data Science 365

11.6.13 Implementing a CPV Framework 365

11.6.14 Risk Assessment and Mitigation 365

11.6.15 Improving Process Robustness 366

11.6.16 Designing Robust Processes 366

11.6.17 Continuous Learning and Adaptation 366

11.6.18 Case Studies 366

11.7 Challenges and Solutions 369

11.8 Future Directions and Trends 374

Bibliography 376

Index 385


Vivek P. Chavda, PhD is an assistant professor in the Department of Pharmaceutics and Pharmaceutical Technology, Lallubhai Motilal College of Pharmacy, Ahmedabad, India. He has over 100 national and international publications, 30 book chapters, ten books, and two patents to his credit. His research interests include the development of biologics processes and formulations, medical device development, nanodiagnostics and non-carrier formulations, long-acting parenteral formulations, and nano-vaccines.

Usha Desai, PhD is a professor and the Dean of Research and Development at the South East Asia College of Engineering and Technology, Bangalore, India. She authored over 50 research articles, five books, and six patents, and has presented technical research papers in numerous international conferences. Her research interests include biomedical signal processing, machine learning, and brain-computer interface.



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