Claverie / Notredame Bioinformatics For Dummies

2. Auflage 2011
ISBN: 978-1-118-05110-8
Verlag: John Wiley & Sons
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 464 Seiten, E-Book

Were you always curious about biology but were afraid to sitthrough long hours of dense reading? Did you like the subject whenyou were in high school but had other plans after you graduated?Now you can explore the human genome and analyze DNA without everleaving your desktop!
Bioinformatics For Dummies is packed with valuableinformation that introduces you to this exciting new discipline.This easy-to-follow guide leads you step by step through everybioinformatics task that can be done over the Internet. Forget longequations, computer-geek gibberish, and installing bulky programsthat slow down your computer. You'll be amazed at all thethings you can accomplish just by logging on and following thesetrusty directions. You get the tools you need to:
* Analyze all types of sequences
* Use all types of databases
* Work with DNA and protein sequences
* Conduct similarity searches
* Build a multiple sequence alignment
* Edit and publish alignments
* Visualize protein 3-D structures
* Construct phylogenetic trees
This up-to-date second edition includes newly created andpopular databases and Internet programs as well as multiple newgenomes. It provides tips for using servers and places to seekresources to find out about what's going on in thebioinformatics world. Bioinformatics For Dummies will showyou how to get the most out of your PC and the right Web tools soyou'll be searching databases and analyzing sequences like apro!

Autoren/Hrsg.

Claverie, Jean-Michel

Notredame, Cedric

Inhaltsverzeichnis

Introduction.
Part I: Getting Started in Bioinformatics.
Chapter 1: Finding Out What Bioinformatics Can Do for You.
Chapter 2: How Most People Use Bioinformatics.
Part II: A Survival Guide to Bioinformatics.
Chapter 3: Using Nucleotide Sequence Databases.
Chapter 4: Using Protein and Specialized Sequence Databases.
Chapter 5: Working with a Single DNA Sequence.
Chapter 6: Working with a Single Protein Sequence.
Part III: Becoming a Pro in Sequence Analysis.
Chapter 7: Similarity Searches on Sequence Databases.
Chapter 8: Comparing Two Sequences.
Chapter 9: Building a Multiple Sequence Alignment.
Chapter 10: Editing and Publishing Alignments.
Part IV: Becoming a Specialist: Advanced BioinformaticsTechniques.
Chapter 11: Working with Protein 3-D Structures.
Chapter 12: Working with RNA.
Chapter 13: Building Phylogenetic Trees.
Part V: The Part of Tens.
Chapter 14: The Ten (Okay, Twelve) Commandments for UsingServers.
Chapter 15: Some Useful Bioinformatics Resources.
Index.

Über Autor(innen)

Jean-Michel Claverie is Professor of Medical Bioinformaticsat the School of Medicine of the Université de laMéditerranée, and a consultant in genomics andbioinformatics. He is the founder and current head of theStructural & Genomic Information Laboratory, located inMarseilles, a sunny city on the Mediterranean coast of France.Using science as a pretext to travel, Jean-Michel has heldpositions in Paris (France), Sherbrooke (PQ, Canada), the SalkInstitute (La Jolla, CA), the Pasteur Institute (Paris), Incytepharmaceutical (Palo Alto, CA); and the National Center forBiotechnology Information (Bethesda, MD). He has used computers inbiology since the early days -- his Ph.D. work involvedmodeling biochemical reactions by programming an 8K Honeywell 516computer right from the console switches! Although he has no clearrecollection of it, he has been credited with introducing theFrench word "bioinformatique" in the late eighties,before involuntarily coining the catchy"bioinformatics" by mistranslating it while giving atalk in English!
Jean-Michel's current research interests are in microbial andstructural genomics, and in the development of bioinformaticmethods for the prediction of gene function. He is the author orcoauthor of more than 150 scientific publications, and a member ofnumerous international review panels and scientific councils. Inhis spare time, he enjoys the relaxed pace of life in Marseilles,with his wife Chantal and their two sons, Nicholas and Raphael.
Cedric Notredame is a researcher at the French NationalCentre for Scientific Research. Cedric has used and abused thefacilities offered by science to wander around Europe. After aPh.D. at EMBL (Heidelberg, Germany) and at the EuropeanBioinformatics Institute (Cambridge, UK) under the supervision ofDes Higgins (yes, the ClustalW guy), Cedric did a post-doc at theNational Institute of Medical Research (London, UK), in the lab ofWillie Taylor and under the supervision of Jaap Heringa. He thendid a post-doc in Lausanne (Switzerland) with Phillip Bucher, andremained involved with the Swiss Institute of Bioinformatics forseveral years. Having had his share of rain, snow, and wind, Cedrichas finally settled in Marseilles, where the sun and the sea aresimply warmer than any other place he has lived in.
Cedric dedicates most of his research to the multiple sequencealignment problem and its many applications in biology. His friendsclaim that his entire life (past, present, future) is somehowstuffed into the T-Coffee multiple-sequence alignment package. Whenhe is not busy dismantling T-Coffee and brewing new sequences,Cedric enjoys life in the company of his wife, Marita.