Dietary Polyphenols and Healthy Aging

From Basic Science to Translational Research
Erscheinungsjahr 2024
ISBN: 978-0-323-95596-6
Verlag: Elsevier Science

Buch, Englisch, 465 Seiten, Format (B × H): 152 mm x 229 mm

Dietary Polyphenols and Healthy Aging: From Basic Science to Translational Research provides a thorough overview of the role of dietary polyphenols as agents to reduce functional decline associated with aging. Polyphenols have an ability to influence some of the common denominators of aging, such as telomere attrition, epigenetic alterations, and mitochondrial dysfunction. In addition, the book discusses the clinical and epidemiological evidence that indicates the consumption of polyphenols may improve a number of health-related variables in older adults.

This book will be a valuable resource for geriatricians, gerontologist and members of nutrition field who are interested in how polyphenols can help to extend the healthy period of life and delay the onset of chronic diseases.

Autoren/Hrsg.

Davinelli, Sergio

Scapagnini, Giovanni

Medoro, Alessandro

Fachgebiete

• Naturwissenschaften Agrarwissenschaften Agrarwissenschaften

Inhaltsverzeichnis

Part 1 Experimental studies 1. Dietary polyphenols: structure, occurrence and bioactivity 2. Polyphenols and hallmarks of aging: an overview 3. Polyphenols, gut microbiota, and aging diseases 4. Polyphenols as hormetins to modulate aging pathways 5. Polyphenols, caloric restriction mimetics and aging process 6. Lifespan and healthspan extension by polyphenols 7. Concluding Remarks

Part 2 Clinical studies 8. Polyphenols, large-scale clinical trials, and aging diseases 9. Flavonoids, atherosclerosis, and cardiovascular disease 10. Polyphenols as neuroprotective agents against brain aging and cognitive impairment 11. Polyphenols and mental health in elderly 12. Polyphenols and frailty status: a focus on mobility performance 13. Polyphenols and type 2 diabetes 14. Polyphenols and cancer 15. Concluding Remarks

Part 3 Epidemiological studies 16. Polyphenols intake and healthy aging diets: A population perspective 17. Polyphenol rich-diets and aging diseases: a focus on Mediterranean diet 18. Polyphenols and all-cause mortality: evidence from epidemiological studies 19. Polyphenols and aging diseases: the Moli-sani study 20. Polyphenols and centenarian populations 21. Polyphenols and menopause: a focus on isoflavones and lignans in population studies 22. Dietary polyphenols and age-related diseases: experimental, epidemiological and clinical trial evidence 23. Concluding Remarks

Über Autor(innen)

Davinelli, Sergio
Sergio Davinelli is assistant professor of clinical biochemistry at the University of Molise, Italy. He completed his postdoctoral work in biochemistry at the University of Maryland School of Medicine and at Harvard T.H. Chan School of Public Health. Research interests concern whether and to what extent dietary polyphenols alleviate the deleterious effects of aging. He has published numerous research papers and reviews in peer reviewed journals and books

Medoro, Alessandro
Alessandro Medoro works in the Department of Medicine and Health, University of Molise, Campobasso, Italy

Scapagnini, Giovanni
Giovanni Scapagnini is professor of human nutrition at the University of Molise, Italy. His research expertise includes elucidating the antioxidant, anti-inflammatory and functional properties of dietary polyphenols, especially in relation to age-related diseases. He has published widely in peer reviewed journals and received several international patents in the fields of medical devices and therapeutic compounds. He was one of the founders of the Italian Society of Nutraceuticals SINut.