Physicochemical Approaches to the Characterization of Pharmaceutical Systems

Erscheinungsjahr 2019
ISBN: 978-0-444-59439-6
Verlag: Elsevier Science

Buch, Englisch, 416 Seiten, Format (B × H): 152 mm x 229 mm

Physicochemical Approaches to the Characterization of Pharmaceutical Systems provides consistent data analysis on the basic physics and chemistry involved in pharmaceutical systems that are carried out using various theoretical models. The book explores states of matter and thermodynamics, how to estimate chemical properties, solubility and distribution phenomena, kinetic processes and drug delivery, and thermodynamics versus the shape of molecules. It supplies several guidelines for achieving better estimations of properties associated with complex molecular geometries, such as important drug, polymer and biopolymer characteristics. Researchers will find it to be a crucial resource for studies in pharmaceutical science and chemical engineering.

Zielgruppe

<p>Primary Market</p> <p>The primary audience is pharmaceutical scientists and chemical engineers, either working the Academy and Industry, as well as to the more sophisticated segments of the manufacturing personnel. <b>Secondary Market</b> <p><b>graduate/research students, as well as for anybody else needing a comprehensive guide which is both rich of theoretical and practical issues.  </b></p>

Autoren/Hrsg.

de Zordi, Nicola

Grassi, Mario

Moneghini, Mariarosa

Grassi, Gabriele

Kikic, Ireneo

Mezzasalma, Stefano

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie

Inhaltsverzeichnis

1. States of matter2. Thermodynamics3. Estimating chemical properties4. Solubility and distribution phenomena5. Kinetic processes and drug delivery6. Thermodynamics versus shape of molecules

Über Autor(innen)

de Zordi, Nicola
Nicola De Zordi (1983) is going to take his Ph.D. within the School of Chemical and Pharmaceutical Sciences and Technologies at the University of Trieste. His expertise is ranging from pharmaceutical chemistry and chemical thermodynamics principles (involved particularly in the preparation of oral solid dosage forms) to their industrial applications. He is the author/coauthor of more than ten publications, published in international journals and conference proceedings, and acting as a referee for the scientific community.

Moneghini, Mariarosa
Prof. M. Moneghini is an Associate Professor and pharmaceutical scientist at the Faculty of Pharmacy of the University of Trieste. From the beginning of 90's years, at the time of her first permanent position, she has been teaching numerous courses for the degree in Pharmacy and in Pharmaceutical Chemistry and Technology. Among the main research topics she is currently working on, the innovative preparation and characterization of modified drug release oral solid dosage forms (tablets, granules, microspheres and extrudes) play a special role. The idea is to benefit in fact from novel and advanced formulation methods, such as microwave irradiation and supercritical fluid techniques, creating a cross-disciplinary environment of pharmaceutical interest. She is also the first author and co-author of more than about one hundred publications, sixty of being published in international journals, and the others appeared both in international and national conference proceedings.