Faderl / Kantarjian Leukemias

Principles and Practice of Therapy
1. Auflage 2010
ISBN: 978-1-4443-2736-6
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 456 Seiten, E-Book

Edited by experts from one of the world's largest leukemiacenters, this book provides information on the biology of thevariety of leukemic disorders, up-to-date diagnostic testing andmany new developments in therapy. Chapters covering new treatmentspresent an outlook for the future and explain the rationale forongoing clinical trials.
Topics include:
* Targeted therapy, e.g. tyrosine kinase inhibitors (Flt3, Aurorakinase inhibitors, kit inhibitors, BCR-ABL inhibitors)
* Ras inhibitors
* Epigenetic therapy (hypomethylaters and histone deacetylaseinhibitors)
* Lenalidomide analogs
* New chemotherapy drugs, e.g. clofarabine, cloretazine,sapacitabine, forodesine
* Combinations of chemotherapy with kinase inhibitors (e.g. ALLinduction protocols in combination with dasatinib or imatinib)
* New monoclonal antibodies (lumiliximab, humaxCD20,anti-CD40)
* Thrombopoietic agents
Leukemias: Principles and Practice of Therapy
* Includes practical information to guide you in challengingsituations, such as treatment of elderly patients, pregnancy,relapsed and refractory disease
* Incorporates chapters on supportive care and pharmacologicinformation about the most frequently used drugs in this area

Autoren/Hrsg.

Faderl, Stefan

Kantarjian, Hagop