Methods for the Study of Microbial Biofilms

Current Trends and Recent Advancements
Erscheinungsjahr 2025
ISBN: 978-0-443-21851-4
Verlag: Elsevier Science

Buch, Englisch, 400 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 450 g

Methods for the study of microbial biofilms: Current Trends and Recent Advancements provides a detailed overview of the latest techniques for the study of biofilms. The book explores a wide range of methods for the characterization and study of cells within biofilms, including microscopy techniques, genomic approaches, transcriptomics, proteomic and proteogenomic tools. Computational and mathematical modelling are also covered. Chapters investigate the physiology of biofilm cells, gene expression pathways related to the formation, maturation and dispersion of biofilms, and molecular factors governing the biofilm formation and development, providing an overview of techniques that can be used at the cellular and molecular level. This book provides a broad overview of the biofilm field, along with the range of techniques that can be used to study and better understand them.

Autoren/Hrsg.

Guldhe, Abhishek

Ravichandran, Vinothkannan

S Kamble, Shashank

Fachgebiete

• Naturwissenschaften Biowissenschaften Molekularbiologie

Inhaltsverzeichnis

1. Microbial biofilms: Occurrence and implications
2. In silico methods to study biofilms
3. In vitro methods to study biofilms
4. Microscopic methods for biofilm analysis
5. In vivo models for biofilms6. Genomic approaches to study biofilms
7. Transcriptomics approaches: qPCR-based techniques
8. Transcriptomics approaches: Microarray and RNA sequencing-based techniques
9. Proteomics studies of biofilms
10. Metabolomics studies
11. Metagenomics/population studies for biofilms
12. Proteogenomic, a latest tool for simultaneous identification of microbial dynamics and proteins involved in biofilm formation
13. Mathematical tools to understand biofilms

Über Autor(innen)

S Kamble, Shashank
Dr. Shashank Kamble holds the expertise in the biology of infectious diseases with an emphasis on tuberculosis & a consistent academic background in microbiology. He holds a PhD from the CSIR-Institute of Genomics & Integrative Biology, New Delhi and a post-doctoral training from the Jawaharlal Nehru University. Currently, he is serving as the Assistant Professor at the Amity Institute of Biotechnology, Mumbai and a visiting scientist at the Advanced Centre for Treatment, Research and Education in Cancer, Mumbai funded by the Dept. of Biotechnology, Government of India. He has several peer reviewed international publications & has delivered invited talks in various academic institutions across the country. He has received research grants from national funding agencies. Currently, He is serving as manuscript reviewer for many international peer reviewed journals such as Frontiers in microbiology, BMC microbiology, Archives of microbiology etc. His research interests include the microbial adaptations inside the hosts as well as the mechanism of anti-microbial resistance & combating strategies.

Ravichandran, Vinothkannan
Dr. Vinothkannan completed his graduation from SASTRA University, Thanjavur, Tamil Nadu, India. He began his research career as a Research Associate at IIT Madras, followed by a postdoctoral fellowship at the Shandong University-Helmholtz Institute of Biotechnology, China. His primary research focuses on drug design targeting quorum sensing pathways in multidrug-resistant bacterial pathogens. He is currently a faculty member at Amity University, Mumbai, where he teaches courses in biochemistry and bioinformatics. Dr. Vinothkannan has authored 56 publications in peer-reviewed journals and is a recipient of several prestigious awards, including the China Postdoctoral Science Foundation Grant, the Shandong University International Exchange Fellowship, the DST-SERB Start-up Research Grant, and the DST NIDHI PRAYAS Grant. In addition to his research and teaching contributions, he serves as an Academic Editor for PLOS ONE and PLOS Pathogens and is also a member of the editorial board of Scientific Reports.