E-Book, Englisch, 284 Seiten
Reihe: Infectious Disease
Hackett / Harn Jr Vaccine Adjuvants
1. Auflage 2007
ISBN: 978-1-59259-970-7
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, 284 Seiten
Reihe: Infectious Disease
ISBN: 978-1-59259-970-7
Verlag: Humana Press
Format: PDF
Kopierschutz: 1 - PDF Watermark
A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.
