Modeling and Control of Infectious Diseases in the Host

With MATLAB and R
Erscheinungsjahr 2019
ISBN: 978-0-12-813052-0
Verlag: Elsevier Science Publishing Co Inc

Buch, Englisch, 256 Seiten, Format (B × H): 231 mm x 190 mm, Gewicht: 554 g

Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.

Autoren/Hrsg.

Hernandez-Vargas, Esteban A.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizinische Mathematik & Informatik
• Mathematik | Informatik Mathematik Numerik und Wissenschaftliches Rechnen Mathematische Modellierung
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Epidemiologie, Medizinische Statistik
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biomathematik

Inhaltsverzeichnis

Part 1. Theoretical Biology Principles1. Introduction2. Mathematical Modeling Principles3. Model Parameter Estimation

Part 2. Modeling Host Infectious Diseases4. Modeling Influenza Virus Infection5. Modeling Ebola Virus Infection6. Modeling HIV Infection7. HIV Evolution During Treatment

Part 3. Advanced Topics in Control Theory8. Optimal Therapy Scheduling9. Suboptimal Therapy Scheduling10. PK/PD-based Impulsive Control

Über Autor(innen)

Hernandez-Vargas, Esteban A.
Dr. Esteban A. Hernandez-Vargas is a Professor at the Frankfurt Institute for Advanced Studies, Germany, and a research group leader and principal investigator at the Institute of Mathematics (UNAM, Mexico). He obtained his Ph.D. in Mathematics from the Hamilton Institute at the National University of Ireland. In July 2014, he founded the pioneering research group of Systems Medicine of Infectious Diseases at the Helmholtz Centre for Infection Research (HZI). He is a member of the Society of Mathematical Biology, the European Society of Virology, and the Mexican Research Council (CONACYT). Additionally, he is an Editorial Board member of Plos One, Journal of Franklin Institute, as well as a Research Topic Editor at Frontiers of Microbiology and Frontiers of Immunology.