Introduction to Cancer Biology

2. Revised Auflage 2023
ISBN: 978-1-316-51261-6
Verlag: Cambridge University Press

Buch, Englisch, 450 Seiten, Format (B × H): 204 mm x 256 mm, Gewicht: 1247 g

From basic principles to insights into pioneering research, this introductory textbook provides the fundamentals of cancer biology that will enable students of biology and medicine to enter the field with confidence. It opens with a discussion of global cancer patterns, how cancers arise, and the risk factors involved. A description of the normal signalling pathways within cells then explains how DNA mutations affect proteins and what this means for the development and behaviour of tumours. Later chapters discuss methods for tumour detection, biomarker identification and the impact of genome sequencing, before reviewing the development of anti-cancer drugs and exciting current advances in treatment. With 50% new material, including two new chapters on genetic analysis of cancer and cancer chemotherapy, improved pedagogy, examples of revolutionising technologies in drug design and delivery, and useful online resources, this textbook offers an accessible and engaging account of cancer biology for undergraduate and graduate students.

Autoren/Hrsg.

Hesketh, Robin

Fachgebiete

• Naturwissenschaften Biowissenschaften Entwicklungsbiologie

Inhaltsverzeichnis

Preface; 1. Lessons from epidemiology; 2. Causes of cancer; 3. Genetic analysis of cancer; 4. Signaling in normal cells; 5. 'Cancer genes': Mutations and cancer development; 6. What is a tumour? 7. Cancer signaling networks; 8. Cancer detection, diagnosis and radiotherapy; 9. Cancer chemotherapy; 10. The future of cancer detection and treatment; Appendix A: Tumour grading and staging; Appendix B: Classes of major oncoproteins; Appendix C: Major tumour suppressor genes; Appendix D: Ten major cancers at a glance; Glossary, References, Index.

Über Autor(innen)

Hesketh, Robin
Robin Hesketh is Emeritus Professor in the Department of Biochemistry, University of Cambridge. He is also a Fellow of Selwyn College. His major research area is anti-angiogenic strategies for cancer therapy. He has lectured in undergraduate and post-graduate courses on cell and molecular biology and cancer and published over 100 research papers and seven books, including the 1st edition of Introduction to Cancer Biology (2012) and Understanding Cancer (2022) for Cambridge University Press.