Jeon International Review of Cell and Molecular Biology

1. Auflage 2011
ISBN: 978-0-12-386044-6
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: 6 - ePub Watermark

E-Book, Englisch, Band Volume 287, 348 Seiten

Reihe: International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology presents current advances and comprehensive reviews in cell biology--both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Impact factor for 2009: 6.088. - Authored by some of the foremost scientists in the field - Provides up-to-date information and directions for future research - Valuable reference material for advanced undergraduates, graduate students and professional scientists

Autoren/Hrsg.

Jeon, Kwang W.

Inhaltsverzeichnis

1;Front Cover;1
2;International Review of Cell and Molecular Biology;4
3;Copyright Page;5
4;Contents;6
5;Contributors;10
6;Chapter 1: Structure and Functions of Aquaporin-4-Based Orthogonal Arrays of Particles;12
6.1;1. Introduction;13
6.2;2. General Properties of OAPs and AQP4;14
6.3;3.OAPs and AQP4 in Cells Outside the Central Nervous System;19
6.4;4. OAPs and AQP4 in Cells of the Central Nervous System;24
6.5;5. OAPs and AQP4 in Reactive Astrocytes, Glioma, and Inflammation;31
6.6;6. Conclusions and Outlook;39
6.7;Acknowledgments;40
6.8;References;40
7;Chapter 2: Interpreting the Stress Response of Early Mammalian Embryos and Their Stem Cells;54
7.1;1. Introduction;58
7.2;2. Stress and Stress Enzymes;58
7.3;3. Stress Responses;63
7.4;4. Roles of Stress Enzymes;72
7.5;5. Models and Lessons;83
7.6;6. Summary, Significance, and Future Studies;91
7.7;Acknowledgments;95
7.8;References;95
8;Chapter 3: Directional Cell Migration: Regulation by Small G Proteins,Nectin-like Molecule-5, and Afadin;108
8.1;1. Introduction;109
8.2;2. Cell Movement;110
8.3;3. Small G Proteins and Leading Edge Structures;117
8.4;4. Nectins, Necls, and Afadin;122
8.5;5. Crosstalk between Growth Factor Receptors and Integrins;130
8.6;6. Regulation of Directionality of Cell Movement;133
8.7;7. Regulation of Dynamics of Cyclical Activation and Inactivation of Small G Proteins by Afadin;136
8.8;8. Concluding Remarks;140
8.9;Acknowledgments;141
8.10;References;141
9;Chapter 4: Mitochondrial RNA Import: FromDiversity of Natural Mechanismsto Potential Applications;156
9.1;1. Introduction;157
9.2;2. RNA Import in Protozoa;160
9.3;3. RNA Import in Plants;167
9.4;4. RNA Import in Fungi;172
9.5;5. RNA Import in Metazoa;177
9.6;6. Potential Applications of Macromolecule Import;184
9.7;7. Conclusion and Prospects;192
9.8;References;193
10;Chapter 5: New Insights into Vinculin Function and Regulation;202
10.1;1. Introduction;203
10.2;2. Vinculin Structure;204
10.3;3. Autoinhibited Conformation and Vinculin Activation;207
10.4;4. Biological Functions;212
10.5;5. Modes of Vinculin Regulation;222
10.6;6. Emerging Themes and Concepts;225
10.7;7. Interplay Between Cell-Cell and Cell-Matrix Adhesion: Vinculin in Development and Cardiomyopathy;230
10.8;8. Conclusions;233
10.9;Acknowledgments;233
10.10;References;233
11;Chapter 6: Nuclear Pore Complex: Biochemistryand Biophysics of NucleocytoplasmicTransport in Health and Disease;244
11.1;1. Introduction;245
11.2;2. What Drives Cargo Transport Through the NPC?;251
11.3;3. Nucleocytoplasmic Transport Pathway;276
11.4;4. NPC and Diseases;278
11.5;5. Conclusion;287
11.6;Acknowledgments;287
11.7;References;288
12;Chapter 7: Dynamic Microtubules and the Texture of Plant Cell Walls;298
12.1;1. Introduction;299
12.2;2. Microtubules;305
12.3;3. The Paradoxical Outer Epidermal Wall;313
12.4;4. Microtubule Alignment and Twisted Growth;315
12.5;5. Microtubule and Microfibril Coalignment;317
12.6;6. (Re)interpreting Wall Patterns;325
12.7;7. A New Dynamic Model for the Influence of Microtubules on the Texture of Plant Cell Walls;330
12.8;8. Concluding Remarks;332
12.9;Acknowledgments;333
12.10;References;333
13;Index;342