Buch, Englisch, 464 Seiten, Format (B × H): 180 mm x 241 mm, Gewicht: 658 g
Reihe: Oxford Higher Education
Buch, Englisch, 464 Seiten, Format (B × H): 180 mm x 241 mm, Gewicht: 658 g
Reihe: Oxford Higher Education
ISBN: 978-0-19-806826-6
Verlag: OXFORD UNIV PR
Exhibits in each chapter that contain additional information and interesting facts
Carefully written chapter summaries to assist quick revision and a comprehensive glossary for quick reference
Presents recent research areas such as regulatory T cells and their manipulation for clinical use and cancer immunotherapy including cancer vaccines
Includes major immunological methods, immunoassays, and experimental systems in the appendix
The early chapters of the book provide a broad overview of the immune system and ist functioning. The subsequent chapters present the importance of discriminating self from non-self through pattern recognition receptors (PRRs), structure and function of antibodies, major histocompatability complex, antigen receptors of the adaptive immune system, cellular interactions that lead to activation of T and B lymphocytes, immune responses against various categories of pathogens, and manipulation of the immune system by vaccination and various vaccine strategies. The book also includes clinically significant areas and hypersensitivity states including allergy, immunodeficiency disorders, transplantation and tumor immunology. There is also a special emphasis om the HIV/AIDS pandemic against which efforts are on at a massive scale. Tolerance and autoimmunity have also been linked for a better understanding of the mechanisms that could lead to autoimmune diseases.
An additional feature of the book is the inclusion of various techniques, immunoassays, and experimental systems provided in the appendix. ELISA and other immunological techniques like agglutination and precipitation having wide ranging applications have also been included in the book.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
1: The immune system - an introduction
2: Innate immune response to infections
3: The lymphoid system and cells of adaptive immunity
4: Antigens and antibodies
5: Major histocompatability complex (MHC)
6: Generation of antibody diversity and B lymphocyte development
7: Cytokines
8: T lymphocyte maturation and activation
9: Effector mechanisms of cell-mediated immunity
10: Activation of B lymphocytes
11: Effector mechanisms of humoral immunity
12: Immune response against microbes
13: Vaccination and vaccine strategies
14: Hypersensitivity reactions
15: Immunologic tolerance and autoimmunity
16: Immunodeficiency diseases
17: Transplantation and graft rejection
18: Tumor immunology
Appendix A Immunological techniques: principles and application
Appendix B Cumulative glossary
