Buch, Englisch, 310 Seiten, Format (B × H): 156 mm x 241 mm, Gewicht: 676 g
Buch, Englisch, 310 Seiten, Format (B × H): 156 mm x 241 mm, Gewicht: 676 g
ISBN: 978-1-56676-810-8
Verlag: Taylor & Francis Inc
Controlled Release Dosage Form Design offers the tools needed to eliminate trial-and error and wasted time and money in controlled release dosage form design! How is this accomplished? By helping the reader UNDERSTAND controlled release technology more quantitatively and mechanistically, thereby creating a "visual" overall picture of the technology.Controlled Release Dosage Form Design is an invaluable tool for all students and professionals in pharmaceutics, chemistry, chemical engineering, biology/biotechnology and medicine. If you are engaged or interested in the development of dosage forms, you will find this book invaluable. You will learn to look at controlled release dosage forms INTERRELATED to each other, rather than piece by piece. You will learn to KNOW how the mechanistic principles which can be applied in dosage forms. Work faster, smarter and with more intuition!
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Weitere Infos & Material
IntroductionConventional vs. Controlled Release Advantages and Disadvantages Pharmacokinetic Considerations of CRDF Polymers as Drug Carriers Classification of CRDFsMonolithic Matrix Controlled SystemsDissolved Drugs Dispersed Drugs Drug-dissolution/diffusion Controlled SystemsMembrane Controlled SystemsConstant Activity Reservoir Non-Constant Activity Reservoir Release of a Drug from a Membrane Reservoir into a Finite Volume Unsteady State Analysis (Time-lag & Burst-effect) Drug Release from Multi-layer Membrane Devices Drug Release from Membrane-matrix Systems Membrane Transport with Bio-conversionSwelling Controlled SystemsMathematical Expression Hydrogel SystemsPolymer Dissolution Controlled SystemsClassification of Polymer Degradation and Erosion Heterogeneous Erosion Homogeneous Erosion Acid Catalyzed Degradation Autocatalyzed Degradation Erosion/Drug Diffusion Controlled Swelling/Erosion Controlled Preparation of Biodegradable MicroparticlesGradient Matrix SystemsMathematical Expression Tablets Hydrogel Beads Granules MegaporousIon Exchange Resin SystemsExchange Process and Equilibrium Ion Exchange Materials Drug Release from Commercial Ion Exchange Resins Highly Swellable Polyelectrolyte Erodible Polyelectrolyte Principle of Diffusion in the Ion Exchange Resin Matrix (Shrinking-core Model) Drug Release in a Limited VolumeOsmotically Controlled SystemsOsmosis Elementary Osmotic Pump (OROS) Solubility Modulated OROS Microporous Osmotic Pump Push-PullGeometrically Modified SystemsPie Shape, Perforated Coated, Donut (Coated/Uncoated), and Multi-hole Frustum and Hemisphere Multi-layer Tablet and Cylinder SystemsOther SystemsHydrodynamically Balanced Systems Oral Time-controlled (Pulsatile) Release SystemsPharmacokinetic Considerations of CRDF DesignOne-compartment Model Two-compartment Model with Zero-order Release Kinetics Pharmacokinetics on Transdermal Delivery Systems In-vitro/In-vivo Correlation
