Kim Marine Microbiology

Bioactive Compounds and Biotechnological Applications
1. Auflage 2013
ISBN: 978-3-527-66528-0
Verlag: Wiley-VCH
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 580 Seiten, E-Book

Deliberately breaking with the classical biology-centered description of marine organisms and their products, this reference emphasizes microbial technology over basic biology, setting it apart from its predecessors. As such, it systematically covers the technology behind high-value compounds for use as pharmaceuticals, nutraceuticals or cosmetics, from prospecting to production issues.

Following a definition of the field, the book goes on to address all industrially important aspects of marine microbial biotechnology. The first main part contains a description of the major production organisms, from archaebacteria to cyanobacteria to algae and symbionts, including their genetic engineering. The remaining four parts look at commercially important compounds produced by these microorganisms together with their applications. Throughout, the emphasis is on technological considerations, and the future potential of these organisms or compound classes is discussed. A valuable and forward-looking resource for innovative biotechnologists in industry as well as in academia.

Autoren/Hrsg.

Kim, Se-Kwon

Inhaltsverzeichnis

PREFACE

INTRODUCTION TO MARINE ACTINOBACTERIA
Introduction
Actinobacteria

Origin and Distribution of Marine Actinobacteria

Isolation and Identification of Marine Actinobacteria

Indigenous Marine Actinobacteria

Role of Actinobacteria in the Marine Environment
Importance of Marine Actinobacteria

Symbioses

Bioinformatics

Conclusions

TREASURE HUNTING FOR USEFUL MICROORGANISMS IN THE MARINE ENVIRONMENT

Introduction

Microorganisms Living in the Marine Environment
Microorganisms Living in Deep Sea Water

STRATEGY OF MARINE VIRUSES IN GLOBAL ECOSYSTEM
Introduction

Reproductive Strategies of Viruses

Abundance of Marine Viruses
Viral Activities in Ecosystems

Recent Advancement of Viruses versus Diseases

The Effect of Ocean Acidification on Marine Viruses

Further Aspects

TAXONOMIC STUDY OF ANTIBIOTIC-PRODUCING MARINE ACTINOBACTERIA

Introduction

Materials and Methods

Result

Discussion

Conclusion

MARINE CYANOBACTERIA: A PROLIFIC SOURCE OF BIOACTIVE NATURAL PRODUCTS AS DRUG LEADS

Introduction

Bioactive Secondary Metabolites from Marine Cyanobacteria
Conclusions

MARINE BACTERIA ARE AN ATTRACTIVE SOURCE TO OVERCOME THE PROBLEMS OF ANTIBIOTIC-RESISTANT STAPHYLOCOCCUS AUREUS
Introduction

Strategies for Overcoming Antibiotic Resistance of Bacteria

Marine Bacteria Are Attractive Natural Sources for Overcoming Antibiotic Resistance of MRSA

MARINE BACTERIA AS PROBIOTICS AND THEIR APPLICATIONS IN AQUACULTURE

Introduction

Definition of Probiotics in Aquaculture

Selecting and Developing Probiotics in Aquaculture

Effects of Probiotics on Aquatic Organisms

Probiotics in the Larviculture 1
Problems Associated with Probiotics Development

Further Work and Conclusions

SMALL-MOLECULE ANTIBIOTICS FROM MARINE BACTERIA AND STRATEGIES TO PREVENT REDISCOVERY OF KNOWN COMPOUNDS

Antibiotic Activity of Marine Bacteria

Structurally Elucidated Marine Bacterial Antibiotics

Cosmopolitan Antibiotics: the Rediscovery Problem

Future Strategies for the Discovery of Marine Bacterial Antibiotics

Conclusions and Perspectives

MARINE BACTERIOPHAGES FOR THE BIOCONTROL OF FISH AND SHELLFISH DISEASES
Introduction

Mode of Action of Phages

Diversity of Marine Phages

Application of Marine Phages to Control Fish and Shellfish Diseases

Potentials and Limitations of Phage Therapy in Marine Fish and Shellfish

MARINE ACTINOMYCETES AS SOURCE OF PHARMACEUTICALLY IMPORTANT COMPOUNDS

Introduction

Marine Actinomycetes as Source of Therapeutics

Marine Actinomycete Compounds as Antibacterials

Marine Actinomycete Compounds as Antitumors/Antiproliferative

Marine Actinomycete Enzymes as Antiproliferatives

Marine Actinomycete Compounds as Antimalarials

Marine Actinomycete Compounds as Antifungals

Bioactive Compounds from Sponge-Associated Actinomycetes

Conclusion

ANTIMICROBIAL AGENTS FROM MARINE CYANOBACTERIA AND ACTINOMYCETES

Introduction

Antimicrobials from Marine Actinomycetes

Antimicrobials from Marine Cyanobacteria
Current Research Status: Challenges and Future Prospects

Conclusions

BIOACTIVE COMPOUNDS FROM MARINE ACTINOMYCETES

Introduction
Actinomycetes

Diversity and Distribution of Marine Actinobacteria

Bioactive Compounds

Conclusions

FUNGAL BIOACTIVE GENE CLUSTERS: A MOLECULAR INSIGHT

Introduction to Fungal Secondary Metabolites

Polyketide Synthase

Nonribosomal Peptide Synthetase

PKS and NRPS Products

Conclusions

ANTICANCER POTENTIALS OF MARINE-DERIVED FUNGAL METABOLITES

Introduction

Marine Fungi

Cancer: Initiation, Progression, and Therapeutics

Anticancer Metabolites of Marine Fungal Origin
Future Prospects and Concluding Remarks

ANTIFUNGAL AND ANTIMYCOTOXIN ACTIVITIES OF MARINE ACTINOMYCETES AND THEIR COMPOUNDS

Introduction

Diversity of Actinomycetes in the Sea

Diversity of Natural Compounds from Marine Actinomycetes
Biological Activities
Conclusions

ANTITUBERCULOSIS MATERIALS FROM MARINE MICROBES

Introduction

Marine Microbe-Derived Antituberculosis Agents

Conclusions

HARNESSING THE CHEMICAL

Über Autor(innen)

Professor Se-Kwon Kim, PhD, currently serves as a senior professor in the Department of Chemistry and the director of the Marine Bioprocess Research Center (MBPRC) at Pukyong National University in the Republic of Korea. He received his BSc, MSc, and PhD from the Pukyong National University and joined as a faculty member. He has previously served as a scientist in the University of Illinois, Urbana
Champaign, Illinois (1988 - 1989), and was a visiting scientist at the Memorial University of Newfoundland in Canada (1999 - 2000).

Professor Se-Kwon Kim was president of the Korean Society of Chitin and Chitosan (1986 - 1990) and the Korean Society of Marine Biotechnology (2006 - 2007). He was also the chairman for the 7th Asia-Pacific Chitin and Chitosan Symposium, which was held in South Korea in 2006. He is one of the board members of the International Society of Marine Biotechnology and the International Society for Nutraceuticals and Functional Foods. Moreover, he was the editor in chief of the Korean Journal of Life Sciences (1995 - 1997), the Korean Journal of Fisheries Science and Technology (2006 - 2007), and the Korean Journal of Marine Bioscience and Biotechnology (2006 - present). His research has been credited with the best paper award from the American Oil Chemist's Society (AOCS) and the Korean Society of Fisheries Science and Technology in 2002. Professor Se-Kwon Kim's major research interests are investigation and development of bioactive substances derived from marine organisms and their application in oriental medicine, nutraceuticals, and cosmeceuticals via marine bioprocessing and mass- production technologies. He has also conducted research on the development of bioactive materials from marine organisms for applications in oriental medicine, cosmeceuticals, and nutraceuticals. To date, he has authored over 500 research papers and holds 110 patents. In addition, he has written or edited more than 40 books.