E-Book, Englisch, Band Volume 82, 253 Seiten, Web PDF
Reihe: Advances in Cancer Research
Klein Advances in Cancer Research
1. Auflage 2001
ISBN: 978-0-08-049023-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, Band Volume 82, 253 Seiten, Web PDF
Reihe: Advances in Cancer Research
ISBN: 978-0-08-049023-6
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papilloma viruses, and modeling prostate cancer in the mouse.
Autoren/Hrsg.
Weitere Infos & Material
1;Cover;1
2;Copyright Page;5
3;Contents;6
4;Contributors to Volume 82;8
5;Chapter 1. Retinoblastoma Protein Partners;10
5.1;I. An Introduction to pRb-Binding Proteins;11
5.2;II. Potential pRb Partners;22
5.3;References;56
6;Chapter 2. p53-Dependent Apoptosis Pathways;64
6.1;I. p53;65
6.2;II. Bcl-2 Family;71
6.3;III. Caspase Family;76
6.4;IV. IAPs;83
6.5;V. p53-Mediated Apoptosis in Cancer Therapy;84
6.6;References;85
7;Chapter 3. von Hippel-Lindau Disease: Clinical and Molecular Perspectives;94
7.1;I. The VHL Gene and VHL Disease;95
7.2;II. The VHL TSG and Sporadic Cancers;103
7.3;III. Functional Analysis of The VHL Tumor Suppressor Gene;104
7.4;IV. Conclusion;110
7.5;References;110
8;Chapter 4. Nitric Oxide-Induced Apoptosis in Tumor Cells;116
8.1;I. Introduction;117
8.2;II. NO and Antimetastatic Resistance;118
8.3;III. Mechanisms of NO-Mediated Apoptosis;125
8.4;IV. Concluding Remarks;133
8.5;References;134
9;Chapter 5. Detection of Minimal Residual Disease;142
9.1;I. Introduction;143
9.2;II. Technical Aspects of the Detection of Minimal Residual Disease;144
9.3;III. MRD in Leukemia;152
9.4;IV. MRD in Lymphoma;166
9.5;V. MRD in Solid Tumors;174
9.6;VI. Concluding Remarks;179
9.7;References;181
10;Chapter 6. Modeling Prostate Cancer in the Mouse;196
10.1;I. Introduction;196
10.2;II. Anatomy of the Adult Prostate Gland;197
10.3;III. Embryology and Growth of the Prostate Gland;198
10.4;IV. Components of the Epithelial Compartment: Do Prostate Stem Cells Exist?;201
10.5;V. Role of Oncogenes and Tumor Suppressors in Prostate Neoplasia;203
10.6;VI. Progress in the Development of CaP Animal Models;206
10.7;References;210
11;Chapter 7. Immunity to Oncogenic Human Papillomaviruses;214
11.1;I. Epidemiology of Human Papillomavirus Infection;215
11.2;II. The Antibody Response to HPV Infection;216
11.3;III. Cellular Immunity to HPV Infection;223
11.4;IV. Does Cross-Protective Immunity Exist?;235
11.5;References;240
12;Index;248
