Kloc / Kubiak Xenopus Development

1. Auflage 2014
ISBN: 978-1-118-49284-0
Verlag: John Wiley & Sons
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 424 Seiten, E-Book

Frogs from the genus Xenopus have long been used as modelorganisms in basic and biomedical research. These frogs have helpedunlock key fundamental developmental and cellular processes thathave led to important scientific breakthroughs and have hadpractical application in embryology, cancer research andregenerative medicine. Xenopus Development is a vitalresource on the biology and development of these key modelorganisms, and will be a great tool to researchers using thesefrogs in various disciplines of biological science.
Xenopus Development is divided into four sections, thefirst three highlight key processes in Xenopus development fromembryo to metamophosis. These sections focus on the cellularprocesses, organogenesis and embryo development. The final sectionhighlights novel techniques and approaches being used in Xenopusresearch.
Providing thorough and detailed coverage, XenopusDevelopment, will be a timely and welcome volume for thoseworking in cell and molecular biology, genetics, developmentalbiology and biomedical research.
* Provides broad overview of the developmental biology of bothXenopus laevis and Xenopus tropicalis
* Explores cellular to systems development in key biomedicalmodel organisms
* Timely synthesis of the field of Xenopus biology
* Highlights key biomedical and basic biological findingsunlocked by Xenopus

Autoren/Hrsg.

Kloc, Malgorzata

Kubiak, Jacek Z.

Inhaltsverzeichnis

Contributors vii
Preface ix
Section I Oocyte and Early Embryo 1
1 Transcription in the Xenopus Oocyte Nucleus 3
Joseph G. Gall
2 RNA Localization during Oogenesis in Xenopus laevis 16
James O. Deshler
3 From Oocyte to Fertilizable Egg: Regulated mRNA Translationand the Control of Maternal Gene Expression 38
Chad E. Cragle & Angus M. MacNicol
4 Polarity of Xenopus Oocytes and Early Embryos 60
Malgorzata Kloc
5 Germ-Cell Specification in Xenopus 75
Mary Lou King
Section II Midblastula Transition, Gastrulation, andNeurulation 101
6 The Xenopus Embryo as a Model System to Study AsymmetricFurrowing in Vertebrate Epithelial Cells 103
Jacek Z. Kubiak, Isabelle Chartrain, & Jean-PierreTassan
7 Induction and Differentiation of the Xenopus CiliatedEmbryonic Epidermis 112
Marie Cibois, Pierluigi Scerbo, Virginie Thomé, AndreaPasini, & Laurent Kodjabachian
8 Wnt Signaling during Early Xenopus Development 130
François Fagotto
9 Neural Tube Closure in Xenopus 163
Hitoshi Morita, Makoto Suzuki, & Naoto Ueno
Section III Metamorphosis and Organogenesis 187
10 Primordial Germ Cell Migration 189
Aliaksandr Dzementsei & Tomas Pieler
11 Development of Gonads, Sex Determination, and Sex Reversal inXenopus 199
Rafa³ P. Piprek & Jacek Z. Kubiak
12 The Xenopus Pronephros: A Kidney Model Making Leaps towardUnderstanding Tubule Development 215
Rachel K. Miller, Moonsup Lee, & Pierre D. McCrea
13 Development of Neural Tissues in Xenopus laevis 239
William A. Muñoz, Amy K. Sater, & Pierre D.McCrea
14 The Development of the Immune System in Xenopus 264
Louis Du Pasquier
15 Neural Regeneration in Xenopus Tadpoles during Metamorphosis293
Mauricio Moreno, Karina Tapia, & Juan Larrain
Section IV Novel Techniques and Approaches 309
16 Atomic Force Microscopy Imaging of Xenopus laevis OocytePlasma Membrane 311
Francesco Orsini
17 Size Scaling of Subcellular Organelles and Structures inXenopus laevis and Xenopus tropicalis 325
Lisa J. Edens & Daniel L. Levy
18 A Model for Retinal Regeneration in Xenopus 346
Masasuke Araki
19 The Xenopus Model for Regeneration Research 368
Ying Chen & Gufa Lin
20 Genomics and Genome Engineering in Xenopus 383
Léna Vouillot, Aurore Thélie, Thibault Scalvenzi,& Nicolas Pollet
Index 403

Über Autor(innen)

Malgorzata Kloc is the Weill Cornell Professor of Cell and Molecular Biology and Director of the Immuno-Biology Laboratory at the Houston Methodist Hospital Research Institute and Adjunct Associate Professor at the University of Texas M D Anderson Cancer Center
Jacek Z. Kubiak is a DR2 Researcher in the CNRS at the Institute of Genetics and Development and at the University of Rennes 1