Buch, Englisch, 288 Seiten, Format (B × H): 173 mm x 245 mm, Gewicht: 517 g
Buch, Englisch, 288 Seiten, Format (B × H): 173 mm x 245 mm, Gewicht: 517 g
ISBN: 978-0-470-84495-3
Verlag: Wiley
The same careful rigour imposed on the design of phase III randomised controlled trials is not always applied to medical research in other areas such as trials conducted at earlier stages of drug development.
With the emphasis that is now placed on evidence-based medicine, such care and rigour will inevitably impact on these areas with increasing attention turned to the quality of design.
This title describes what principles can be used to structure research effectively allowing for the required degree of accuracy.
Written by two best selling authors, this book includes many examples from medical literature and will be of great value to all groups conducting studies at the interface of clinical and laboratory research.
Autoren/Hrsg.
Fachgebiete
Weitere Infos & Material
Preface ix
Chapter 1 What is Evidence? 1
Chapter 2 Measurement, Forms and Questionnaires 18
Chapter 3 Principles of Study Size Calculation 37
Chapter 4 Randomisation 59
Chapter 5 Cross-sectional and Longitudinal Studies 78
Chapter 6 Surveys, Cohort and Case–Control Studies 109
Chapter 7 Clinical Trials–General Issues 139
Chapter 8 Early Clinical Trials 160
Chapter 9 Phase III Trials 188
Chapter 10 Diagnosis 209
Chapter 11 Prognostic Factor Studies 227
References 246
Tables 255
Index 267
