Marx / Müller-Hermelink Epithelial Tumors of the Thymus

Pathology, Biology, Treatment
Erscheinungsjahr 2013
ISBN: 978-1-4899-0033-3
Verlag: Springer US
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 399 Seiten, eBook

Zielgruppe

Research

Autoren/Hrsg.

Marx, Alexander

Müller-Hermelink, Hans Konrad

Inhaltsverzeichnis

I. Histological and Immunological Characterization of Thymic Epithelial Tumors and Their Differential Diagnoses.- 1. Classification of Thymic Epithelial Neoplasms.- 2. Thymic Carcinoma.- 3. Thymoma/Thymic Carcinoma: A Distinctive, Unusual Morphologic Entity.- 4. A Clinicopathological Study of Thymomas in Singapore.- 5. Thymoma: A Clinicopathologic Study of 60 Cases.- 6. p53-Alterations in Thymic Epithelial Tumors.- 7. p53 Protein Expression in Thymic Epithelial Tumors.- 8. p53 Overexpression and Thymoma Prognosis.- 9. Metallothionein Expression in Thymomas: A Tumor Marker for Spindle and Squamoid Thymoma Cells.- 10. Cytokeratin (CK) Profile in Thymomas: CK 10 Is a Marker for Cortical Thymomas and CK 20 a Marker for Medullary Thymomas.- 11. Neuroendocrine Differentiation in Thymic Epithelial Tumors: Immunohistochemical Studies.- 12. Microscopic Thymoma and Myasthenia Gravis: A Clinicopathological and Immunohistochemical Study of Two Cases.- 13. Complex and Differential Cytokeratin Profiles in Thymomas and Correlation with Normal Thymus.- 14. Unusual Recurrence of Mixed Thymoma in Breast.- 15. Histiocytosis -X of the Thymus: Development of Myelomonocytic Leukemia 5 Years after Thymectomy.- II. Altered T Cell Functions in Thymic Epithelial Tumors.- 16. T Cell Development in the Human Thymus.- 17. Intrathymic Autoantigens and Their Role in the Shaping of the Autoimmune T Lymphocyte Repertoire.- 18. T Cell Epitopes of the Acetylcholine Receptor and the Pathogenesis of Myasthenia Gravis.- 19. Thymus in Thymoma-Associated Myasthenia Gravis: Transplantation of Thymoma and Extrathymomal Thymic Tissue into SCID Mice.- 20. Thymic Tumor Progression in SV40T Transgenic Mice Model: Suggestion of Thymoma—Thymic Carcinoma Sequence.- 21. Analysis of a Murine Thymic CarcinogenesisModel Induced by the Expression of Large T of SV40.- 22. Inefficient Positive Selection of CD4+ T Cells in Epithelial Cell Tumors of the Human Thymus.- 23. Abnormal T Lymphocyte Development in Myasthenia Gravis-Associated Thymomas.- 24. Oligoclonal Peripheral T-Cell Lymphocytosis as a Result of Aberrant T-Cell Development in a Cortical Thymoma.- 25. Estrogens Modulate IL-6 Production by Cultured Normal and Pathological Human Thymic Epithelial Cells.- III. Paraneoplastic Autoimmunity.- 26. Thymoma and Autoimmune Neurological Disorders: A Search for Missing Links in Pathogenesis.- 27. T-Cell Derived Mechanisms in the Pathogenesis of Myasthenia Gravis.- 28. Thymomas Express Ryanodine Receptor Epitopes.- 29. Titin Epitope in Thymoma.- 30. Accessory Molecule Expression in Human Thymomas and Thymus.- 31. CD40-Expression in Thymoma.- 32. Myasthenia Gravis with Thymoma and Fas Antigen.- 33. Myasthenia Gravis Patients Have a Cellular Immune Response against Titin.- 34. Tumor Necrosis Factor Gene Polymorphisms in Thymoma and Non-Thymoma Myasthenia Gravis.- IV. Diagnosis and Therapy of Thymic Epithelial Tumors.- 35. Clinical Immunology of Thymic Tumors in Patients with Myasthenia Gravis.- 36. Myasthenia Gravis with Thymoma.- 37. Reproducibility of a Histogenetic Classification of Thymic Epithelial Tumours.- 38. Morphology of Thymic Remnants Removed after Video-Assisted Thoracoscopic Extended Thymectomy in Patients with Thymomatous Myasthenia Gravis.- 39. Core Needle Biopsy of Anterior Mediastinum Masses.- 40. Cyclin-Dependent Kinase 6 (PLSTIRE) Expression in Normal Thymus, Thymomas, and T-Cell Lymphoblastic Lymphoma.- 41. Our Approach in the Preparation for Thymectomy in Myasthenia Gravis.- 42. Onset of Myasthenia Gravis after Thymectomy for Thymoma.- V. Management of Thymectomized Patients.- 43. Aspects of Clinical Preparation of Thymectomy in Myasthenic Cases with or without Thymoma and the Clinico-Biological Follow-up of the Thymectomized Patients.- 44. Long-Term Prognosis of Patients with Thymoma-Associated Myasthenia Gravis.- 45. Thymoma and Myasthenia Gravis: Incidence of Tumor Recurrences in 126 Patients.- 46. Thymoma—Prognostic Factors and Outcome.- 47. Management of Thymectomised Myasthenic Patients.- 48. Management of Thymectomized Myasthenic Patients.- 49. Therapeutic Options in Locally Advanced Thymoma.- 50. The Role of Radiotherapy in Treatment of Thymoma.- Authors and Sponsors.