Stroke Genetics

2. Auflage 2017
ISBN: 978-3-319-85854-8
Verlag: Springer International Publishing

Buch, Englisch, 431 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 749 g

This revised, expanded second edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genomewide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed.

Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Meschia, James F.

Sharma, Pankaj

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Vorklinische Medizin: Grundlagenfächer Humangenetik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

Introduction.- Familial stroke epidemiology.- Association study results.- GWAS.- Aneurysms/carvernous/AVM.- ICH/amyloid/microbleeds.- CADASIL.- Fabry.- MELAS.- Sickle.- Other monogenic.- White matter disease.- Carotid atherosclerosis.- Dissection.- Pharmacogenomics.- Non-Caucasian stroke genetics.- Small vessel disease.- Genetics of neuroimaging in stroke.- Cerebrovenous thrombosis.- Ethics.

Über Autor(innen)

Pankaj Sharma, MD, PhD, FRCP

Reader & Consultant Neurologist

Imperial College London & Hammersmith Hospitals

London, UK

James F. Meschia, MD

Chair, Department of Neurology

Mayo Clinic

Jacksonville, Florida, USA