Morrison | Hypothalamus: Brainstem Interactions in Homeostasis | Buch | 978-0-387-29083-6 | www.sack.de

Buch, Englisch, 350 Seiten, GB, Format (B × H): 165 mm x 241 mm

Morrison

Hypothalamus: Brainstem Interactions in Homeostasis


Erscheinungsjahr 2008
ISBN: 978-0-387-29083-6
Verlag: Springer

Buch, Englisch, 350 Seiten, GB, Format (B × H): 165 mm x 241 mm

ISBN: 978-0-387-29083-6
Verlag: Springer


In recent years, there has been a resurgence of research interest in the role of the hypothalamus in a variety of regulatory and behavioral functions, from feeding and energy homeostasis to circadian rhythms, thermoregulation and blood pressure control. Nearly every homeostatic function influenced by the hypothalamus is subject to a dysregulation that becomes manifest in a disease process. Elucidating the neuropharmacology of the hypothalamic-brainstem circuits that play such a significant role in homeostatic regulation can contribute to the design of novel therapeutic approaches. In assembling the most recent knowledge about the structural and functional organization of hypothalamic-brainstem autonomic pathways regulating homeostasis and reproduction, this book provides a unique opportunity to appreciate the multifaceted role of hypothalamic neural circuits in maintaining homeostasis, to understand the critical role played by hypothalamic-brainstem interactions and to recognize the many parallels in organization and occurrences of cross-talk among the hypothalamic regulatory systems

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Zielgruppe


Researchers, Clinical researchers and Graduate students in Neurobiology, Pharmacology, Anatomy, Physiology and Physiological Psychology

Weitere Infos & Material


Hypothalamus-brainstem pathways.- Hypothalamic projections to brainstem nuclei.- Hypothalamic peptidergic inputs to the brainstem

Fluid and blood pressure regulation.- Hypothalamic - brainstem pathways in the modulation of baroreceptor reflex function.- Median preoptic, Paraventricular nucleus – osmotic regulation, Ang II, renal sympathetic, fluid balance.- Paraventricular nucleus – brainstem autonomic mechanisms in heart failure

Stress responses.- Dorsomedial hypothalamus – pons/raphe in heart rate and defense response.- Dorsomedial hypothalamus – brainstem in the regulation of ACTH release

Temperature regulation.- Preoptic and dorsomedial hypothalamus – brainstem in thermogenesis.- Hypothalamus – brainstem in cutaneous vasoconstriction.- Posterior hypothalamus – brainstem in shivering

Energy homeostasis.- Arcuate – paraventricular – lateral hypothalamus interactions with brainstem circuits in regulation of food intake.- Hypothalamus – nucleus of the tractus solitarius in satiety/appetite.- Hypothalamus – brainstem influences on blood glucose.- Hypothalamus – brainstem in energy expenditure

Regulation of pelvic organs.- Preoptic hypothalamus – Barrington’s in micturition.- Preoptic hypothalamus – raphe in reproduction

Circadian and sleep regulation.- Dorsomedial hypothalamus – brainstem in circadian rhythms.- Lateral hypothalamus (orexin) – brainstem in sleep regulation.- Hypothalamus – brainstem in pineal (melatonin) regulation

Respiratory regulation.- Hypothalamic - brainstem pathways in the control of respiration.- Hypothalamic - brainstem pathways in the modulation of chemoreceptor reflex function



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