The Choroid Plexus and Cerebrospinal Fluid

Emerging Roles in CNS Development, Maintenance, and Disease Progression
Erscheinungsjahr 2015
ISBN: 978-0-12-801740-1
Verlag: Elsevier Science

Buch, Englisch, 210 Seiten, Format (B × H): 155 mm x 231 mm, Gewicht: 454 g

The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines new and established work to allow for cross-disciplinary discussion and showcase newfound excitement surrounding the choroid plexus and cerebrospinal fluid (CSF). This book is of great utility to neuroscientists interested in biological questions about cancer, multiple sclerosis, Alzheimer's, choroid plexus, or CSF research, and especially for researchers looking to expand their research into later stages of their disease of interest, such as metastasis. No other resource is currently available which addresses these issues in this fashion. The focus on the choroid plexus provides a practical resource on modeling clinical issues influenced by this brain region for researchers from students to principal investigators.

Zielgruppe

<p>Graduate students in biological and biomedical sciences, post-doctoral students and fellows, as well as all researchers and clinicians seeking a resource on the interactions of choroid plexus, cerebrospinal fluid during normal development, maintenance of brain microenvironment and neurodegenerative diseases (Multiple Sclerosis and Alzheimer's Disease) and brain tumors (primary and metastatic). </p>

Autoren/Hrsg.

Neman, Josh

Chen, Thomas C.

Fachgebiete

• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Neurologie, Klinische Neurowissenschaft

Inhaltsverzeichnis

1. Introduction to the Ventricular System and Choroid Plexus Tatsuhiro Fujii, Joshua Youssefzadeh, Michael Novel and Josh Neman

2. Development of brain ventricles and choroid plexus Ellen M. Carpenter

3. Choroid plexus: Structure and Function Florence M. Hofman and Thomas C. Chen

4. Towards an artificial choroid plexus, concept and clinical implications Thomas Brinker and John Morrison

5. Choroid Plexus Tumors Sean A. Grimm and Marc C. Chamberlain

6. Role of Blood Brain Barrier, Choroid Plexus, and Cerebral Spinal Fluid in Extravasation and Colonization of Brain Metastases Cecilia Choy and Josh Neman

7. The Role of the Choroid Plexus in the Pathogenesis of Multiple Sclerosis Vahan Martirosian, Alex Julian and Josh Neman

8. The Choroid Plexus and Cerebrospinal Fluid system: roles in neurodegenerative diseases Jérôme Badaut and Jean-François Ghersi-Egea

9. Delivery Considerations for Targeting the Choroid Plexus-Cerebrospinal Fluid Route Thomas C. Chen

Glossary

Über Autor(innen)

Chen, Thomas C.
Dr. Chen is currently Professor of Neurological Surgery and Pathology at the University of Southern California. Highly experienced in the area of translational research aimed at the development of clinical trials and novel therapeutics for malignant brain tumours, he is the head of the Glioma Research Group at USC. He completed his neurological surgery residency and PhD in pathobiology at the University of Southern California, followed by fellowship training in spinal surgery from the Medical College of Wisconsin. Dr. Chen is a physician, a board certified neurosurgeon, and the Director of Surgical Neuro-oncology - recognized both for his skills as a neurosurgeon and his cutting edge research examining glioma biology.