Hydrogels of Cytoskeletal Proteins

Preparation, Structure, and Emergent Functions
Softcover Nachdruck of the original 1. Auflage 2016
ISBN: 978-3-319-80125-4
Verlag: Springer

Buch, Englisch, 79 Seiten, Previously published in hardcover, Format (B × H): 155 mm x 235 mm, Gewicht: 454 g

This book describes a new family of bio-polymer gels made from cytoskeletal proteins - actin, microtubule, and tropomyosin.  The importance of the gel state with multi-scale hierarchical structure is emphasized to utilize emergent functions in living organisms. Detailed protocol of gel preparation, specified method of structure investigation, and dynamic studies of self-organization, self-healing, synchronized oscillating, and autonomous motility functions are introduced  together with biomimetic functions of synthetic hydrogels.

Zielgruppe

Research

Autoren/Hrsg.

Osada, Yoshihito

Kawamura, Ryuzo

Sano, Ken-Ichi

Fachgebiete

• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde Materialwissenschaft: Biomaterialien, Nanomaterialien, Kohlenstoff
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik
• Naturwissenschaften Chemie Organische Chemie Polymerchemie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Naturwissenschaften Physik Angewandte Physik Biophysik

Inhaltsverzeichnis

Introduction.- Microtubules Gel.- Actin Gel.- Tropomyosin Gel. Conclusion.

Über Autor(innen)

Professor Yoshihito Osada obtained his Bachelor’s
degree in chemistry from Waseda University, Japan, and received his Ph.D. in
polymer science from Moscow State University (supervisor: Prof. V.A. Kabanov).
He began as a professor in 1992, then became the Dean and eventually the Vice President of Hokkaido
University, Sapporo, Japan. He was invited to be Deputy Director at the Advanced
Science Institute, RIKEN in 2007. He is currently a Senior Visiting Scientist at
RIKEN and a professor emeritus at Hokkaido University.

Professor Yoshihito Osada is a pioneer of polymer gels. He developed artificial muscle systems
using various functional gels such as Shape Memory Gel and Double Network Gel
with excellent mechanical performances. His current interests focus on highly-hierarchical protein gels with “emergent”
muscle functions, nano-patterning of the gel, and electro-conductive gels.


Ken-Ichi Sano
received his B.S. degree in biologyfrom Osaka City University, Japan, in
1993, and his Ph.D. degree in biophysics from Nagoya University, Japan, in
2000. In 1994, he joined the International Institute for Advanced Research,
Panasonic, and since 1999 he has worked for RIKEN, Harima Institute at SPring-8.
Since 2003 he has been with the Department of Protein Engineering, Cancer
Institute, Japanese Foundation for Cancer Research, where
he studied interfacial molecules between biomaterials and inorganics. In 2008,
he joined the Molecular and System Life Science Unit, Advanced Science Institute,
RIKEN as a Contract Researcher, and became Deputy Unit Leader in 2009 where he
studied hydrogels of cytoskeletal proteins. In April 2011 he joined the Department of Innovative Systems Engineering, Nippon Institute of Technology as
an Associate Professor. His current research interests include cellular drug
delivery systems and evaluation of antidepressant agents using novel models.

Ryuzo Kawamura
wasborn in Nara, Japan, in 1980. He obtained his Bachelor’s degree in
bioengineering from Tokyo Institute of Technology, Japan, in 2005 and received
his Ph.D. in polymer science from Hokkaido University, Japan
(supervisor: Prof. J.P. Gong) in 2008. He did postdoctoral research at RIKEN
and at the National Institute of Advanced Science and Technology (AIST). Currently,
he is an Assistant Professor in Department of Chemistry, Saitama University,
Japan.

In 2009, he joined the Molecular and System Life Science Unit, Advanced
Science Institute, RIKEN. There he developed the Multi-scale Hierarchical
Supra-Macromolecular Gels (MHSMG) as a new type of material. His current
research interest is in coordinative and mesoscale functions of the
cytoskeletal and motor proteins with both viewpoints of material science and
biology.