Patsalos Antiepileptic Drug Interactions

A Clinical Guide
Third Auflage 2016
ISBN: 978-3-319-32909-3
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 340 Seiten

This updated third edition of a successful book is a description of both pharmacokinetic and pharmacodynamic antiepileptic drug (AED) interactions, including details of the magnitude and mechanism of interactions, and also of drug combinations that are not associated with interactions and therefore can be coprescribed without undue concern. Presented in alphabetical order and by drug class, drug interactions that occur between AEDs and also between AEDs and non-AEDs are described in three sections: Drug interactions between AEDs; Drug interactions between AEDs and non-AED Drugs: Interactions affecting AEDs; Drug interactions between AEDs and non-AED Drugs: Interactions affected by AEDs.

Antiepileptic Drug Interactions: A Clinical Guide, 3rd Edition with its clear, concise and unambiguous content will 

allow physicians and allied health professionals to make more rational choices when AED polytherapy regimens are indicated. There is always a choice and avoiding highly interacting drugs and choosing drug combinations that are minimally interacting or do not interact should be the goal in treating patients with epilepsy. This book provides all the necessary information so as to allow this goal to be achieved and, if necessary, to aid effective management of AED interactions.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Patsalos, Philip N.

Inhaltsverzeichnis

Section 1 – Introduction.- Section 2 – Drug Interactions Between AEDs.- Acetazolamide.- Carbamazepine.- Clobazam.- Clonazepam.- Ethosuximide.- Eslicarbazepine acetate.- Felbamate.- Gabapentin.- Lacosamide.- Lamotrigine.- Levetiracetam.- Methsuximide.- Oxcarbazepine.- Perampanel.- Phenobarbital.- Phenytoin.- Piracetam.- Pregabalin.- Primidone.- Retigabine.- Rufinamide.- Stiripentol.- Tiagabine.- Topiramate.- Valproic Acid.- Vigabatrin.- Zonisamide.- Section 3 – Drug Interactions between AEDs and non-AED drugs: Interactions Affecting AEDs.- Acetazolamide.- Carbamazepine.- Clobazam.- Clonazepam.- Ethosuximide.- Eslicarbazepine acetate.- Felbamate.- Gabapentin.- Lacosamide.- Lamotrigine.- Levetiracetam.- Methsuximide.- Oxcarbazepine.- Perampanel.- Phenobarbital.- Phenytoin.- Piracetam.- Pregabalin.- Primidone.- Retigabine.- Rufinamide.- Stiripentol.- Tiagabine.- Topiramate.- Valproic Acid.- Vigabatrin.- Zonisamide.- Section 4 – DrugInteractions between AEDs and non-AED drugs: Interactions Affected by AEDS.- Analgesics.- Antimicrobials.- Antineoplastic agents.- Antiulcer drugs.- Cardiovascular drugs.- Immunosuppressants.- Neuromuscular Blocking Agents.- Psychotropic Drugs.- Steroids.- Miscellanea.

Über Autor(innen)

Philip N. Patsalos, FRCPath, PhD

Professor of Clinical Pharmacology/Consultant Clinical Pharmacologist

Institute of Neurology/The National Hospital for Neurology and Neurosurgery, Queen

Square, London and the Epilepsy Society, Chalfont St Peter, UK