Peer Handbook of Harnessing Biomaterials in Nanomedicine

Preparation, Toxicity, and Applications
Erscheinungsjahr 2012
ISBN: 978-981-4364-27-0
Verlag: Pan Stanford Publishing
Format: PDF
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 424 Seiten

This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Zielgruppe

Advanced undergraduate- and graduate-level students in nanotechnology; researchers in macromolecular science, nanotechnology, chemistry, biology, and medicine, especially those with an interest in drug delivery, cancer therapy, inflammation, RNAi, imaging with nanocarriers, and immuno-nanotoxicity.

Autoren/Hrsg.

Peer, Dan

Fachgebiete

• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie Biotechnologie: Mikrotechnologie, Nanobiotechnologie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe

Inhaltsverzeichnis

Biomaterial-Based Particulate Drug Carriers, R. Margalit
Single-Chain Polymer Nanoparticles for Application in Nanomedicine, I. Loinaz
Polyethylene Glycol Polyester Block Co-Polymers: Biocompatible Carriers for Nanoparticulate Drug Delivery, M. L. Forrest
Recent Progress in Polymer Therapeutics as Nanomedicines, R. Satchi-Fainaro
Polysaccharides as Nanomaterials for Therapeutics, D. Peer
RNAi as New Class of Nanomedicines, D. M. Dykxhoorn
Novel RNA Interference (RNAi)-Based Nanomedicines for Treating Viral Infections, P. Kumar
Detection and Description of Tissue Disease: Advances in the Use of Nanomedicine for Medical Imaging, J. L. Dearling and A. B. Packard
Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery, M. Weil
Wrong Resemblance? Role of the Immune System in the Biocompatibility of Nanostructured Materials, T. Vorup-Jensen
Complement Activation, Immunogenicity and Immune Suppression as Potential Side Effects of Liposomes, J. Szebeni and Y. Barenholz
The Story of DOXIL — A Personal Account, Y. Barenholz

Über Autor(innen)

Dan Peer is a principal investigator and a senior lecturer and leads an NIH-funded laboratory at Tel Aviv University, Israel. Dan completed his education in biochemistry and biophysics from Tel Aviv University, Israel. From January 2005 to August 2008, he worked at Harvard Medical School. He joined the Department of Cell Research and Immunology, in the Faculty of life sciences at Tel Aviv University in September 2008 to establish the laboratory of nanomedicine. Dan’s research was between the first to demonstrate systemic delivery of RNAi using targeted nano-carriers to the immune system and the first to utilize RNAi for in vivo validation of new drug targets within the immune system. His work was published in premier scientific journals such as Science, Nature Nanotechnology, and PNAS. He is the editor and author of several books in the field of nanomedicine, an associate editor of Journal of Biomedical Nanotechnology, and Frontiers in Biotechnology and Drug Delivery, and on the editorial board of the journals Nanotechnology and Journal of Controlled Release. Dan has received more than 20 awards and honors.