E-Book, Englisch, Band Volume 9, 303 Seiten, Web PDF
Pelletier Alkaloids: Chemical and Biological Perspectives
1. Auflage 2017
ISBN: 978-1-4832-8784-3
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark
E-Book, Englisch, Band Volume 9, 303 Seiten, Web PDF
Reihe: Alkaloids: Chemical and Biological Perspectives
ISBN: 978-1-4832-8784-3
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark
This monograph series provides unprecedented interdisciplinary coverage of research relating to the chemistry and biological properties of alkaloids - a class of biologically active compounds of more than 10,000 members. Timely, comprehensive and authoritative, the series features chapters on chemical properties and structure elucidation, synthesis, biosynthesis, taxonomy, spectroscopy, pharmacology, toxicology, and X-ray crystallography of alkaloids. The chapters are written and reviewed by eminent researchers, all of them acknowledged experts in the field. Subject and organism indexes are included for each volume.
Autoren/Hrsg.
Weitere Infos & Material
1;Front Cover;1
2;Alkaloids: Chemical and Biological Perspectives;4
3;Copyright Page;5
4;Table of Contents;16
5;Dedication;6
6;Contributors;8
7;Preface;10
8;Contents of Previous Volumes;12
9;Chapter One. Taxol;18
9.1;1. INTRODUCTION;19
9.2;2. DISCOVERY OF TAXOL;20
9.3;3. STRUCTURE DETERMINATION OF TAXOL;21
9.4;4. APPROACHES TO THE SUPPLY OF TAXOL;25
9.5;5. MECHANISM OF ACTION OF TAXOL;31
9.6;6. STRUCTURE ACTIVITY RELATIONSHIPS (SAR) OF TAXOLAND ANALOGS;32
9.7;7. CLINICAL RESULTS;34
9.8;REFERENCES;36
10;Chapter Two. The Synthesis of Macroline Related Sarpagine Alkaloids;40
10.1;1. INTRODUCTION;41
10.2;2. SYNTHESIS;47
10.3;3. BIOLOGICAL ASPECTS OF ALKALOIDS;90
10.4;4. SUMMARY;94
10.5;REFERENCES;96
11;Chapter Tree. Erythrina Alkaloids;102
11.1;1. INTRODUCTION;103
11.2;2. OCCURRENCE AND ISOLATION;104
11.3;3. STRUCTURE DETERMINATION;113
11.4;4. ABNORMAL ERYTHRINA ALKALOIDS;125
11.5;5. BIOSYNTHESIS;129
11.6;6. SYNTHESIS;133
11.7;7. PHARMACOLOGY;163
11.8;8. REFERENCES;164
12;Chapter Four. Chemistry, Biology and Chemoecology of the Pyrrolizidine Alkaloids;172
12.1;1. INTRODUCTION;173
12.2;2. SURVEY AND CLASSIFICATION OF PLANT PAs;173
12.3;3. BIOSYNTHESIS OF THE NECINE BASES;179
12.4;4. BIOSYNTHESIS OF THE NECIC ACIDS;185
12.5;5. TRANSPORT, STORAGE AND METABOUSM OF PAs IN PLANTS;187
12.6;6. ROLE OF THE PA W-OXIDES IN PLANTS;189
12.7;7. ACTIVITIES OF PLANT PAs;191
12.8;8. ROLE OF PAs IN PLANT - INSECT - RELATIONSHIPS;192
12.9;9. THELOUNES;202
12.10;10. CONCLUSIONS;203
12.11;REFERENCES;205
12.12;APPENDIX I;214
12.13;APPENDIXE II;227
13;Chapter Five. Alkaloids from Cell Cultures of Aspidosperma Quebracho-Bianc;252
13.1;1. INTRODUCTION;253
13.2;2. SIGNIFICANCE OF ASPIDOSPERMA QUEBRACHO-BIANCO PLANTS;253
13.3;3. ESTABLISHMENT OF TISSUE AND CELL CULTURES;255
13.4;4. ISOLATION AND STRUCTURE OF ALKALOIDS;256
13.5;5. CONCLUSIONS AND FUTURE ASPECTS;261
13.6;REFERENCES;262
14;Chapter Six. Fumonisins;264
14.1;1. INTRODUCTION;265
14.2;2. FUMONISIN STRUCTURES AND OCCURRENCE;266
14.3;3. ANALYSIS, ELUCIDATION OF STRUCTURES AND REACTIONS;269
14.4;4. BIOSYNTHESIS OF THE FUMONISINS;283
14.5;5. BIOLOGICAL EFFECTS OF FUMONISINS;285
14.6;6. RELATED COMPOUNDS;286
14.7;SUMMARY;291
14.8;REFERENCES;292
15;Subject Index;296
16;Organism Index;302
