Radosavljevic Assessing Human Exposure to Key Chemical Carcinogens

Diagnostic Approaches and Interpretation
1. Auflage 2025
ISBN: 978-3-031-84441-6
Verlag: Springer International Publishing
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 207 Seiten

This book introduces an effective, affordable, non-invasive, and quick method to detect exposure to dangerous chemical carcinogens, which cause life-threatening conditions like cardiovascular, endocrine, neurological, hematological, dermatological, and malignant diseases. Nearly 20 million people are diagnosed with cancer annually, with almost 10 million deaths. While eliminating carcinogens completely is impossible, improving detection and monitoring—especially through specialized urine analysis—can help define preventive measures to lower carcinogen levels in the body.

The chemical carcinogens discussed have been used for decades without proper evaluation of their health effects, costing millions of lives. Considering the long-term health impacts of current products is critical. Early detection is crucial as most carcinogens have cumulative effects. Identifying urinary markers of exposure can help detect, eliminate, or reduce sources of carcinogens, advancing preventive oncology.

The book focuses on Group 1 chemical carcinogens classified by the International Agency for Research on Cancer (IARC). The described methods are highly effective, affordable, and applicable in any location with HPLC (High-Performance Liquid Chromatography) and ICP (Inductively Coupled Plasma) devices. They are non-invasive, requiring only urine samples, quick, and inexpensive.

This volume aims to develop, improve, and implement screening methods for malignant diseases. It supports medical professionals in interpreting HPLC and ICP urinary analyses and providing guidance on reducing or avoiding carcinogen exposure. In some cases, doctors may identify sources of exposure and inform authorities to address and eliminate these hazards.

Zielgruppe

Professional/practitioner

Autoren/Hrsg.

Radosavljevic, Vladan

Inhaltsverzeichnis

Introduction.- Arsenic.- Cadmium.- Nickel.- Beryllium.- Chromium hexavalent.- Aflatoxins.- 4- Aminobiphenyl.- Aristolochic acids.- Benzene.- Benzidine.- Benzo[a]pyrene.-Bis(chloromethyl) ether (BHME) and Chloromethyl methyl ether (HMME).- 1,3-Butadiene.- Vinyl chloride.- 1,2-dichloropropane.- Ethylene oxide.- Lindane (gamma hexachlorocyclohexane – ?-HHCH).- 4,4'-methylenebis(2-chloroaniline).- 2-naphthylamine (2-NA).- Orthotoluidine.- Pentachlorophenol.- Polychlorinated biphenyls (PHBs).- Polycyclic aromatic hydrocarbons (shale oil).- Polycyclic aromatic hydrocarbons (soot).- Polycyclic aromatic hydrocarbons (coke production).- Polycyclic aromatic hydrocarbons (occupational exposure during coal tar distillation).- Polycyclic aromatic hydrocarbons (emissions from burning coal indoors).- 2,3,7,8-Tetrachlorodibenzo-para-dioxin.- 2,3,4,7,8-Pentachlorodibenzofuran.- Trichlorethylene.

Über Autor(innen)

Vladan Radosavljevi? graduated from the Medical Faculty of the University of Belgrade, Serbia, in 1991. He specialized (May 1995) and received his doctorate (November 1999) in epidemiology at the Medical Faculty of the University of Belgrade.  Dr. Radosavljevi? was the head of the Department of Epidemiology and deputy director of the Military Institute for Preventive Medicine in Belgrade from 2003 to 2010. He was the head of military preventive medicine from 2010 to 2020 in the Ministry of Defense of Serbia, and in 2020 he moved to the Institute of Epidemiology of the Military  Medical  Academy, Belgrade, where he works as an expert epidemiologist. As a scientist, he was also a professor at the Biological Weapons course at the Military Academy of the University of Defense in Belgrade and a research associate at the Epidemiology course. Since 2015, Dr. Radosavljevi? is a United Nations expert on biological weapons within the mechanism of the United Nations Secretary General. This volume is his third book with Springer.