Rahman / Choudhary / Perry Recent Advances in Medicinal Chemistry, Volume 1

1. Auflage 2015
ISBN: 978-0-12-803962-5
Verlag: Elsevier Science & Techn.
Format: EPUB
Kopierschutz: Adobe DRM (»Systemvoraussetzungen)

E-Book, Englisch, 486 Seiten

Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more. - Edited and written by leading experts in medicinal chemistry research - Reviews recent advances in the field, including the characterization of inorganic nanomaterials as therapeutic vehicles - Covers a variety of topical areas, such as HPLC and in the analysis of tricyclic antidepressants in biological samples, and tannins and their influence on health

Autoren/Hrsg.

Rahman, Atta-Ur

Choudhary, Muhammad Iqbal

Perry, George

Leseproben

List of Contributors
Amalia Bosia     Department of Oncology, Biology and Biochemistry, Research Center on Experimental Medicine (CeRMS), University of Torino, Via Santena 5/bis, 10126 Torino, Italy Ann Nowé     Computational Modeling Lab (CoMo), Department of Computer Sciences, Faculty of Sciences, VrijeUniversiteit Brussel, Pleinlaan 2, B-1050 Brussel, Belgium Anna Hošt’álková     Department of Pharmaceutical Botany and Ecology, ADINACO Research Group, Faculty of Pharmacy, Charles University, Hradec Kralove, Czech Republic and Centro de Investigación del Proyecto CAMINA A.C., Mexico City, Mexico Antonio Ibarra     Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, Huixquilucan, Estado de México, Mexico Charles Y.F. Young     Departments of Urology, Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesot, USA Chiara Riganti     Department of Oncology, Biology and Biochemistry, Research Center on Experimental Medicine (CeRMS), University of Torino, Via Santena 5/bis, 10126 Torino, Italy Christopher Bachran     Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D-12200 Berlin, Germany D. Del Principe     Department of Experimental Medicine & Surgery, University of Rome ‘Tor Vergata’, Italy Daniel Jun     Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic Dario Ghigo     Department of Oncology, Biology and Biochemistry, Research Center on Experimental Medicine (CeRMS), University of Torino, Via Santena 5/bis, 10126 Torino, Italy Diana Bachran     Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D-12200 Berlin, Germany Dipak Dasgupta     Biophysics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata 700 064, India E. De Azambuja     Medical Oncology Clinic, Jules Bordet Institute, Boulevard de Waterloo, 125, 1000 Brussels, Belgium E. Minenza     S.C. Oncologia Medica, Ospedale Civile, Via Santa Lucia 2, 62100 Macerata, Italy Elisabetta Aldieri     Department of Oncology, Biology and Biochemistry, Research Center on Experimental Medicine (CeRMS), University of Torino, Via Santena 5/bis, 10126 Torino, Italy Fabio Polticelli     Dipartimento di Biologia, Università Roma Tre, V.le Marconi 446, 00146 Rome, Italy; Dipartimento di Biologia, Università Roma Tre, V.le Marconi 446, 00146 Rome, Italy and Istituto Nazionale di Fisica Nucleare, Sezione Rome Tre, 00146 Rome, Italy Federica Sinibaldi     Dipartimento di Scienze Cliniche e Medicina Traslazionale, Università di Roma ‘Tor Vergata’, Via Montpellier 1, 00133, Rome, Italy George Perry     College of Sciences, University of Texas at San Antonio, San Antonio, Texas, USA H.-Q. Yuan     Institute of Biochemistry and Molecular Biology, Medical College, Shandong University, Jinan, People’s Republic of China Hendrik Fuchs     Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D-12200 Berlin, Germany Hirak Chakraborty     Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA Humberto Mestre     Facultad de Ciencias de la Salud, Universidad Anàhuac México Norte, Huixquilucan, Estado de México, Mexico I. Savini     Department of Experimental Medicine & Surgery, University of Rome ‘Tor Vergata’, Italy I.N. Papadoyannis     Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 541 24, Greece Ivana Campia     Department of Oncology, Biology and Biochemistry, Research Center on Experimental Medicine (CeRMS), University of Torino, Via Santena 5/bis, 10126 Torino, Italy J.-Y. Zhang     Institute of Biochemistry and Molecular Biology, Medical College, Shandong University, Jinan, People’s Republic of China Jakub Chlebek     Department of Pharmaceutical Botany and Ecology, ADINACO Research Group, Faculty of Pharmacy, Charles University, Hradec Kralove, Czech Republic K.V. Donkena     Departments of Urology and Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota, USA Kamil Kuca     Centre of Advanced Studies, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic Katerina Macáková     Department of Pharmaceutical Botany and Ecology, ADINACO Research Group, Faculty of Pharmacy, Charles University, Hradec Kralove, Czech Republic Kunihiro Tsuchida     Division for Therapies against Intractable Diseases, Institute for Comprehensive Medical Science (ICMS), Fujita Health University, Toyoake, Aichi 470-1192, Japan Luciana Avigliano     Department of Experimental Medicine & Surgery, University of Rome ‘Tor Vergata’, Italy Laura Fiorucci     Dipartimento di Scienze Cliniche e Medicina Traslazionale, Università di Roma ‘Tor Vergata’, Via Montpellier 1, 00133, Rome, Italy Lubomír Opletal     Department of Pharmaceutical Botany and Ecology, ADINACO Research Group, Faculty of Pharmacy, Charles University, Hradec Kralove, Czech Republic Lucie Cahlíková     Department of Pharmaceutical Botany and Ecology, ADINACO Research Group, Faculty of Pharmacy, Charles University, Hradec Kralove, Czech Republic M. Nunzi     S.C. Oncologia Medica, Azienda Ospedaliera, Via Tristano di Joannuccio 1, 05100 Terni, Italy Maria Aparecida Nagai     Disciplina de Oncologia, Departamento de Radiologia e Oncologia da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455, 4 °andar, CEP 01246-903, São Paulo, Brazil and Laboratório de Genética Molecular do Centro de Investigação Translacional em Oncologia, Av. Dr. Arnaldo, 251, 8 andar, CEP 01246-000, São Paulo, Brazil M.K. Nika     Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, 541 24, Greece M.-L. He     Institute of Cancer Research, Life Science School, Tongji University, Shanghai, People’s Republic of China M.M. Brentani     Disciplina de Oncologia, Departamento de Radiologia e Oncologia da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455, 4 °andar, CEP 01246-903, São Paulo, Brazil M.V. Catani     Department of Experimental Medicine & Surgery, University of Rome ‘Tor Vergata’, Italy Mariantonietta Colozza     S.C. Oncologia Medica, Azienda Ospedaliera, Via Tristano di Joannuccio 1, 05100 Terni, Italy Mark Sutherland     University of Bradford, Institute of Cancer Therapeutics, Bradford, West Yorkshire, United...