Buch, Englisch, 341 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 8123 g
Buch, Englisch, 341 Seiten, HC runder Rücken kaschiert, Format (B × H): 183 mm x 260 mm, Gewicht: 8123 g
Reihe: Methods in Pharmacology and Toxicology
ISBN: 978-1-4939-6659-2
Verlag: Springer
Authoritative and cutting-edge, Stem Cell-Derived Models in Toxicology serves as a vital resource for researchers aiming to improve risk assessment in drug discovery and design.
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Professional/practitioner
Autoren/Hrsg.
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Weitere Infos & Material
Stem Cell-Derived Models for Safety and Toxicity Assessments: Present and Future Studies in the “Proclinical Space”.- Human Pluripotent Stem Cell Test for Assessing the Potential Teratogen Risk.- Cardiac Action Potential Measurement in Human Embryonic Stem Cell Cardiomyocytes for Cardiac Safety Studies Using Manual Patch-Clamp Electrophysiology.- Automated Patch Clamp Recordings of Human Stem Cell-Derived Cardiomyocytes.- The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential.- Optogenetic Approach to Cardiotoxicity Screening: Simultaneous Voltage and Calcium Imaging Under Paced Conditions.- HTS Compatible Voltage- and Ca2+-Sensitive Dye Recordings from hiPSC-Derived Cardiomyocytes Using the Hamamatsu FDSS Systems.- Kinetic Image Cytometry for Predicting Arrhythmias Using Human Stem Cell-Derived Cardiomyocytes.- Decoding Ca2+ Signals as a Non-Electrophysiological Method forAssessing Drug Toxicity in Stem-Cell Derived Cardiomyocytes.- Combined Impedance and Extracellular Field Potential Recordings from Human Stem Cell-Derived Cardiomyocytes.- Edge Detection for Contractility Measurements with Cardiac Spheroids.- Contractile Force Readout of hESC-Cardiomyocytes.- In Vitro Cardiotoxicity Investigation Using High Content Analysis and Human Stem Cell-Derived Models.- Structural Toxicity: Hypertrophy Models of Human Pluripotent Stem Cell-Derived Cardiomyocytes.- Addressing Functional Neurotoxicity Using the Microelectrode Array (MEA).- Micropatterned Co-Cultures of Induced Pluripotent Stem Cell-Derived Hepatocytes and Stromal Cells for Drug Toxicity Studies.