Harnessing Quorum Quenching for Disease Management

Erscheinungsjahr 2026
ISBN: 978-0-443-34178-6
Verlag: Elsevier Science

Buch, Englisch, 400 Seiten, Format (B × H): 191 mm x 235 mm

Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.

Autoren/Hrsg.

Roy, Arpita

Policarpo Tonelli, Fernanda Maria

Pandit, Soumya

Fachgebiete

• Naturwissenschaften Biowissenschaften Mikrobiologie
• Naturwissenschaften Biowissenschaften Zellbiologie

Inhaltsverzeichnis

PART 1: Understanding quorum quenching
1. Quorum sensing and quorum quenching: a brief review
2. Quorum quenching enzymes and inhibitor
3. Methods to study quorum quenching
4. Quorum sensing inhibitors from natural sources
5. Mechanisms of quorum quenching

PART 2: Quorum quenching applications
7. Inhibiting quorum sensing for antimicrobial resistance
8. Inhibiting quorum sensing for disease treatment
9. Genetically modified organisms to produce quorum quenching enzymes
10. Quorum quenching bacteria and their application in the medical field
11. Quorum quenching for biocontrol of plant diseases

PART 3: Quorum quenching: new technologies, limitation and future prospects
12. Nanomaterials for quorum quenching
13. In silico technologies and synthetic biology role in quorum quenching
14. Main limitations and future prospects of quorum quenching strategies

Über Autor(innen)

Pandit, Soumya
Dr. Soumya Pandit is a senior assistant professor at Sharda University, Greater Noida, Delhi NCR, India. He pursued his doctoral studies from Indian Institute of Technology, Kharagpur and completed his postdoctoral research work (PBC fellow) at the Department of Desalination and Water Treatment, The Zuckerberg Institute for Water Research (ZIWR), Ben-Gurion University of the Negev. He is a recipient of North West University, South Arica Post-doctoral fellowship. He has authored 21 research papers in peer-reviewed journals and has authored 22 book chapters and published 3 Indian patents. He holds a BTech and MTech in Biotechnology. His current research focuses on microbial electrochemical systems for bioenergy harvesting, biohythane, bacterial biofilm and biofouling study, etc. He serves as a reviewer for Frontiers in Environmental Microbiology, editorial board member in SCIREA Journal of Biology, and the Journal of Korean Society of Environmental Engineers (JKSEE).

Policarpo Tonelli, Fernanda Maria
Dr. Fernanda Maria Policarpo Tonelli (Ph.D) is specialized in biotechnology/molecular biology and has been studying nanomaterials applications such as delivery and remediation. She has worked with engineered viral particles and nanomaterials functionalized by different protocols (gold nanorods, carbon nanotubes, carbon-dots, nanoparticles, nanographene oxide) that resulted in 10 patent applications. She teaches topics related to biochemistry and biotechnology/molecular biology to graduate students as an associate professor at Federal University of São João del Rei. Dr. Tonelli has edited and/or authored 3 books, has reviewed various articles/book proposals, has authored 12 scientific articles and more than 20 book chapters from international publishers. The main topics addressed in the publications are: nanomaterials, gene delivery strategies, remediation strategies and cell signaling. She has presented and participated in numerous national and international conferences and has also had the opportunity to contribute to the organization of various scientific events. Dr. Tonelli has also dedicated herself to promote Science and Technology co-funding an ONG with this purpose and also joining a scientific divulgation group composed only by women. She has had her efforts as a researcher recognized by various awards (including For Women in Science Brazil-L'Oreal/UNESCO/ABC and Under30 Brazil - Forbes) and certificates of merit.

Roy, Arpita
Dr. Arpita Roy (Ph.D) is working as an Assistant Professor in Sharda University, Greater Noida, India. Her specialization is in plant biotechnology, nanobiotechnology, environmental biotechnology and microbiology. She has been teaching graduate and post graduate students of biotechnology. She has taught topics related to plant biotechnology, microbiology, bioprocess engineering and solid waste management. She has authored more than 50 scientific articles and 18 book chapters from international publishers and edited 2 books. She has presented and participated in numerous state, national and international conferences, seminars, workshops and symposium. She has received the Commendable Research Award for excellence in research during the year 2019 and 2020- DTU. She has served as editorial board member and reviewer of reputed international journals.