Non-Enzymatic Protein Modifications in Health, Disease and Ageing

Erscheinungsjahr 2020
ISBN: 978-0-12-814305-6
Verlag: Elsevier Science

Buch, Englisch, 252 Seiten, Format (B × H): 191 mm x 235 mm, Gewicht: 504 g

Non-Enzymatic Protein Modifications in Health, Diseases and Ageing discusses each type of non-enzymatic protein, introducing non-enzymatic protein modifications, reviewing the state-of-the-art, and presenting updates and current trends. The book covers various aspects of the subject, including the formation and removal of modified proteins, their roles in disease, preventative methods, and possible roles in cellular signaling. This book not only provides well-established facts, but also discusses current hypotheses and controversies.

Zielgruppe

<p>Early-career researchers in biochemistry, biophysics, cell biology, biological chemistry, and food chemistry; Advanced researchers in aligned fields looking to update their knowledge of protein modifications.</p>

Autoren/Hrsg.

Sadowska-Bartosz, Izabela

Bartosz, Grzegorz

Fachgebiete

• Naturwissenschaften Physik Angewandte Physik Biophysik
• Naturwissenschaften Biowissenschaften Angewandte Biologie Biophysik

Inhaltsverzeichnis

1. Chemistry of non-enzymatic protein modifications2. Methods for detection and quantification of non-enzymatic protein modifications3. Non-enzymatic protein modifications under physiological conditions4. Possible role of non-enzymatic protein modifications in cellular signalling5. Altered non-enzymatic protein modifications in diseases and their pathogenic roles6. Accumulation of products of non-enzymatic protein modification in aging and their potential role in aging7. Prevention of non-enzymatic protein modifications and of their effects8. Non-enzymatic protein modifications during food and feed preparation and storage, and their effect on food and feed quality9. Summary: what to expect?

Über Autor(innen)

Bartosz, Grzegorz
Grzegorz Bartosz is a Professor and Head of the Molecular and Biophysics Department, and the Department for Membrane Biophysics at the Faculty of Biology and Environmental Protection at the University of Lodz in Poland. He has published widely in the field.

Sadowska-Bartosz, Izabela
Izabela Sadowska-Bartosz is Assistant Professor in the Department of Biochemistry and Cell Biology, at the University of Rzeszów in Poland. Her research focusses on non-enzymatic protein modifications, their roles in disease and aging, and their prevention. She has published widely on the topic, and received the title of Dr.habil for her work on 'Prevention of selected non-enzymatic modifications of proteins by natural and synthetic antioxidants'