Nitrogen Heterocycles in Cancer Therapy

Erscheinungsjahr 2025
ISBN: 978-0-443-33106-0
Verlag: Elsevier Science

Buch, Englisch, 260 Seiten, Format (B × H): 216 mm x 276 mm

Nitrogen Heterocycles in Cancer Therapy offers an in-depth exploration of the latest nitrogen-containing heterocyclic compounds used in the fight against cancer. Across ten chapters, the book lays a solid foundation in oncology while delving into the design, synthesis, and anticancer mechanisms of these compounds. Drawing from current research, it examines how these molecules are engineered to target cancer cells, and highlights both in-vitro and in-vivo evaluation techniques. Through clear explanations and detailed analysis, the book provides readers with a comprehensive understanding of molecular strategies and promising new agents shaping modern cancer therapy.

In addition to covering the science behind these compounds, the book presents clinical study reports demonstrating their effectiveness across various cancer types. It also discusses the global market impact, pharmacoeconomics, and future directions for drug development. By integrating the latest advancements and practical insights, this work stands out as an invaluable resource for researchers, clinicians, and students seeking to stay at the forefront of innovative cancer treatments.

Autoren/Hrsg.

Sahu, Sanjeev Kumar

Vaidya, Ankur

Fachgebiete

• Naturwissenschaften Biowissenschaften Biowissenschaften

Inhaltsverzeichnis

1. Introduction to heterocyclic nucleus-based nitrogen-containing anticancer compounds
2. Three and Four-Member Nitrogen-Containing Heterocyclic Compounds as Anticancer Agents
3. Five membered nitrogen-containing heterocyclic compounds (pyrrole and pyrazole derivatives) as anticancer compounds
4. Six membered nitrogen-containing heterocyclic compounds (Pyridine, pyrimidine, piperidine and triazine) as anticancer compounds
5. Azoles (triazole and imidazole) scaffolds in anticancer drug design
6. Purine derivatives in cancer therapy
7. Indole scaffolds in anticancer drug discovery
8. Benzimidazole, benzothiazole and benzoxazole derivatives as potential anticancer agents
9. Quinoline, isoquinoline and quinoxaline derivatives as promising anticancer agents
10. Miscellaneous fused heterocyclic compounds (?-lactam derivatives, Carbazoles, Isatin derivatives, Pyrrolo-Benzodiazepines, Pyrido[2,3-d] Pyrimidine Derivatives) as anticancer compounds

Über Autor(innen)

Sahu, Sanjeev Kumar
DR.Sanjeev Sahu received his PhD in Pharmaceutical Sciences at Dr. H. S. Gour Vishwavidyalaya, Saga, India. He is currently Professor at Lovely Professional University. He published dozens of research publications in the SCI/ Scopus indexed renowned international as well as national journals. He also published several books and book chapters.

Vaidya, Ankur
Dr. Ankur Vaidya did his graduation, post-graduation and PhD from Dept. of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar (M.P.) in 2004, 2008 and 2013 respectively. Dr. Vaidya has a teaching and research experience of many years and is currently working as Asst. Professor in Faculty of Pharmacy UPUMS, Saifai, Etawah (U.P.) India. Dr. Ankur has a key research interest in discovery of new anticancer agents with novel targets and published dozens outstanding publications in various International journals. Dr Vaidya has credited as reviewer of international journals of repute in the field of Pharmaceutical sciences. Dr. Ankur has guided several postgraduate theses and was also the recipient of AICTE-NDF (National Doctorate Fellowship) fellowship for PhD research project. Dr. Vaidya has published nternational book chapters, one International book authored and 1 national book. Dr. Ankur has participated/presented in various National and International conferences.