Drug Delivery Using Nanomaterials

1. Auflage 2022
ISBN: 978-0-367-76793-8
Verlag: CRC Press

Buch, Englisch, 430 Seiten, Format (B × H): 161 mm x 240 mm, Gewicht: 810 g

Reihe: Emerging Materials and Technologies

After the drug discovery and development process, designing suitable formulations to safely deliver the optimum dose, while avoiding side effects, has been a constant challenge, especially when drugs are very toxic and have poor solubility and undesirable clearance profiles. With recent advances in synthetic technologies, nanoparticles can be custom-made from a variety of advanced materials to mimic the bioenvironment and can be equipped with various targeting and imaging moieties for site-specific delivery and real-time imaging. Drug Delivery Using Nanomaterials covers advancements in the field of nanoparticle-based drug-delivery systems, along with all the aspects needed for a successful and marketable nanoformulation.

FEATURES

- Offers a general overview of the entire process involved in the synthesis and characterization of pharmaceutical nanoparticles

- Covers a broad range of synthetic materials for developing nanoformulations customized for specific disease states, target organs, and drugs

- Every chapter sequentially builds, providing a progressive pathway from classical nanoparticles to the more advanced to be used as a full drug product by consumers

- Provides information in a bottom-up manner in that definitions and explanations of relevant background information serve as a framework for understanding advanced concepts

This user-friendly reference is aimed at materials engineers, chemical engineers, biomedical engineers, pharmaceutical scientists, chemists, and others working on advanced drug delivery, from academia as well as industry.

Zielgruppe

Academic

Autoren/Hrsg.

Shahzad, Yasser

Rizvi, Syed A. A.

Yousaf, Abid Mehmood

Hussain, Talib

Fachgebiete

• Technische Wissenschaften Maschinenbau | Werkstoffkunde Technische Mechanik | Werkstoffkunde
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizinische Fachgebiete Pharmakologie, Toxikologie
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Pharmazie
• Technische Wissenschaften Sonstige Technologien | Angewandte Technik Medizintechnik, Biomedizintechnik
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Medizin, Gesundheitswesen Medizintechnik, Biomedizintechnik, Medizinische Werkstoffe
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Biotechnologie
• Technische Wissenschaften Verfahrenstechnik | Chemieingenieurwesen | Biotechnologie Verfahrenstechnik, Chemieingenieurwesen

Inhaltsverzeichnis

1. Introduction to Nanomaterials for Drug Delivery 2. Manufacturing Techniques for Nanoparticles in Drug Delivery 3. Pharmacokinetics of Nanomaterials/Nanomedicines 4. Bioinspired Nano-Formulations: Materials, Approaches, and Applications in Drug Delivery 5D-Printed Nanocrystals for Oral Administration of the Drugs 6. Functional Nanomaterials 7. Trigger-Sensitive Nanoparticle for Drug Delivery. 8. Metal Organic Frameworks for Drug Delivery 9. Graphene and Graphene-Based Nanomaterials: Current Applications and Future Perspectives 10. Nanomaterials for Lungs Targeting 11. Nanostructured Drug Carriers for Nose-to-Brain Drug Delivery: A Novel Approach for Neurological Disorders 12. Carbon Nanotubes in Cancer Therapy 13. Applications of Silica-Based Nanomaterials for Combinatorial Drug Delivery in Breast Cancer Treatment 14. Cationic Gemini Surfactants as Genes and Drug Carriers 15. Stability of Nanomaterials 16. Nanotoxicology and Regulatory Aspects of Nanomaterials and Nanomedicines

Über Autor(innen)

Dr. Yasser Shahzad is an Assistant Professor at Department of Pharmacy, COMSATS University Islamabad (CUI), Lahore Campus. Dr. Yasser won a prestigious Nicholson Scholarship to pursue PhD from University of Huddersfield, UK. He also remained a Postdoctoral Fellow at PHARMACEN, North-West University South Africa. He has a particular interest in advanced drug delivery research at the interface of pharmaceutics, chemistry and cosmetics, and publishes regularly in internationally recognized peer-reviewed journals. He has authored more than 60 research publications in high quality international journals, including three book chapters in books published by CRC Press, Springer Nature and Wiley. He also serves as Editorial Board member of various international journals. Dr. Yasser holds active research collaborations with various international universities in UK, US and South Africa.

Dr. Syed A.A. Rizvi is Assistant Professor, Pharmaceutical Sciences, Hampton University. He has published over 200 peer-reviewed articles, including journal publications, book chapters, books, US patents, and oral/poster presentations. He also serves on the Editorial Boards/Panels of different journals (in various capacities) and review manuscripts and books for over 150 well known scientific publications (journals and books). Dr. Rizvi enjoys teaching and engaging students in thought process, beside creative cooking at home and practicing martial arts (1st degree black belt in Okinawan Goju Ryu Karate).

Dr. Abid Mehmood Yousaf is presently working as an Assistant Professor of Pharmacy at Department of Pharmacy, COMSATS University Islamabad, Lahore campus. Before this, he has also worked for more than two years at the same position in the Faculty of Pharmacy, University of Central Punjab, Lahore. He has earned his degree of Doctor of Pharmacy (Pharm-D) from University of the Punjab in 2009. In 2011, he was enrolled in MS-PhD program at College of Pharmacy, Hanyang University, South Korea. He has performed his research in the Lab of Physical & Industrial Pharmacy under the supervision of Prof. Dr. Han-Gon Choi, a distinguished professor of Pharmacy in South Korea. He was awarded with the degree of PhD in Pharmacy in 2015. Dr. Abid has numerous publications in peer-reviewed SCI journals of pharmacy. He has presented his research work at several international conferences abroad. He vows to continue research in the same field and train young pharmacist researchers.

Dr. Talib Hussain has been working as Assistant Professor in Department of Pharmacy, COMSATS University Islamabad (CUI), Lahore campus since 2018. Prior to join CUI, he served in Primary & Secondary Health Department Punjab as Deputy Drug Controller/ Provincial Drug Inspector. He obtained Pharmacy (2006) and M. Phil (2009) degrees from Bahauddin Zakariya University Multan. He received his PhD in Pharmacy from University of Huddersfield, UK in 2014. Primary research work of his PhD was based on formulation development of poorly soluble drugs through bespoke Microwave technique. Moreover, isothermal titration calorimetry was employed to investigate the drug-excipient compatibility. Over the years, he has developed active collaborations and expertise in the field of drug delivery such as solid dispersions, nano-particles, micro-emulsions, liposomes, hydrogels for oral as well as for topical drug delivery systems. He has published more than 40 articles in the form of original research, reviews and book chapters.