Principles of Mucosal Immunology

1. Auflage 2012
ISBN: 978-0-8153-4443-8
Verlag: Taylor & Francis Inc

Buch, Englisch, 552 Seiten, Format (B × H): 212 mm x 277 mm, Gewicht: 1094 g

Principles of Mucosal Immunology is designed for graduate students and postdoctoral fellows, researchers in immunology and microbiology, and medical and dental students. It presents the basic and clinical aspects of the mucosal immune system, focusing on the major components of the mucosal barrier—the gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems. Topics include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. Principles of Mucosal Immunology is sponsored by the Society for Mucosal Immunology and is written by internationally recognized leaders in the field.

Autoren/Hrsg.

Smith, Phillip D.

MacDonald, Thomas T.

Blumberg, Richard S.

Fachgebiete

• Interdisziplinäres Wissenschaften Wissenschaften: Allgemeines
• Medizin | Veterinärmedizin Medizin | Public Health | Pharmazie | Zahnmedizin Klinische und Innere Medizin Immunologie

Inhaltsverzeichnis

I. Development and Structure of Mucosal Tissue 1. Overview of the Mucosal Immune System Structure2. Phylogeny of the Mucosal Immune System3. Immunological and Functional Differences Among Individual Compartments of the Mucosal Immune System4. Secreted Effectors of the Innate Mucosal Barrier
II. Cellular Constituents of Mucosal Immune Systems and Their Function in Mucosal Homeostasis 5. Immune Function of Epithelial Cells6. Intraepithelial Lymphocytes: Unusual T Cells at Epithelial Surfaces7. Lymphocyte Populations within the Lamina Propria8. Mucosal B Cells and Their Function9. Secretory Immunoglobulins and Their Transport10. Role of Dendritic Cells in Integrating Immune Responses to Lumenal Antigens11. Intestinal Macrophages in Defense of the Mucosa12. Mucosal Basophils, Mast Cells, and Eosinophils13. M Cells and the Follicle-Associated Epithelium14. Lymphocyte Trafficking from Inductive Sites to Effector Sites15. Mucosal Tolerance
III. Microbial Commensalism 16. Recognition of Microbe-Associated Molecular Patterns by Pattern Recognition Receptors17. The Commensal Micorbiota and Its Relationship to Homeostasis and Disease
IV. Genitourinary Tract 18. The Immune System of the Genitourinary Tract19. Mucosal Immune Responses to Microbes in the Genitourinary Tract
V. Nose, Airways, Oral Cavity, and Eyes 20. Immunobiology of the Nose, Upper Airways, and Oral Cavity21. Bronchial Associated Lymphoid Tissue and Immune-mediated Respiratory Diseases22. The Ocular Surface as a Mucosal Immune Site
VI. Infectious Diseases of Mucosal Surfaces 23. Mucosal Interactions with Enteropathogenic Bacteria24. Heliobacter pylori Infection25. Viral Infections26. Infection-driven Periodontal Disease27. Vaccine Strategies for Mucosal Infections
VII. Specific Immune-mediated Diseases of Mucosal Surfaces 28. Celiac Disease29. IgA Nephropathy30. Mucosal Manifestations of Immunodeficiencies31. Inflammatory Bowel Disease32. Food Sensitive and Eosinophilic Enteropathies

Über Autor(innen)

The Society for Mucosal Immunology advances research and education related to the field of mucosal immunology.
Phillip D. Smith, MD, is Professor of Medicine and Microbiology and The Mary J Bradford Professor of Gastroenterology, Department of Medicine at the University of Alabama at Birmingham, Alabama.
Thomas T. MacDonald, PhD, FRCPath, FMedSci, is Dean for Research and Professor of Immunology, Centre for Immunology and Infectious Disease, at Barts and the London School of Medicine and Dentistry, London.
Richard S. Blumberg, MD, is Professor of Medicine, Harvard Medical School, Chief, Gastroenterology and Hepatology Division, Brigham and Women’s Hospital,Boston, Massachusetts.