Stuart The Chemistry of Natural Products: 6

Plenary Lectures Presented at the Sixth International Symposium on the Chemistry of Natural Products
1. Auflage 2013
ISBN: 978-1-4832-8467-5
Verlag: Elsevier Science & Techn.
Format: PDF
Kopierschutz: 1 - PDF Watermark

E-Book, Englisch, 178 Seiten, Web PDF

The Chemistry of Natural Products: 6 discusses some of the advances in the chemistry of sesquiterpenic lactones. This book presents the studies on terpenoids isolated from Compositae. Organized into 10 chapters, this book begins with an overview of the revised structures of some guaianolides and germacranolides. This text then examines the advances in the field of steroidal alkaloids and sapogenins possessing the C27-carbon skeleton of cholestane. Other chapters consider the usefulness of steroidal glycosides of digitalis as life-saving products. This book discusses as well the microbiological oxidation of the five-membered ether sesquiterpenes guaioxide and liguroxide using Mucor parasiticus. The final chapter deals with the application of hypofluorites, particularly trifluoromethyl hypofluorite, in the synthesis of fluorinated steroids. This book is a valuable resource for organic chemists, phytochemists, plant biochemists, botanists, and other scientists. Students and research workers who are interested in the chemistry of natural products will also find this book extremely useful.

Dr. Sam Stuart is a physiotherapist and a research Fellow within the Balance Disorders Laboratory, OHSU. His work focuses on vision, cognition and gait in neurological disorders, examining how technology-based interventions influence these factors. He has published extensively in world leading clinical and engineering journals focusing on a broad range of activities such as real-world data analytics, algorithm development for wearable technology and provided expert opinion on technology for concussion assessment for robust player management. He is currently a guest editor for special issues (sports medicine and transcranial direct current stimulation for motor rehabilitation) within Physiological Measurement and Journal of NeuroEngineering and Rehabilitation, respectively.

Autoren/Hrsg.

Stuart, Sam

Inhaltsverzeichnis

1;Front Cover;1
2;The Chemistry of Natural Products 6;4
3;Copyright Page;5
4;Table of Contents;6
5;CHAPTER 1. RECENT STUDIES ON SESQUITERPENES;8
5.1;ABSTRACT;8
5.2;INTRODUCTION;8
5.3;APPENDIX;13
5.4;References;14
6;CHAPTER 2. RECENT ADVANCES IN THE CHEMISTRY OF PLANT STEROIDS;16
6.1;ABSTRACT;16
6.2;INTRODUCTION;16
6.3;STEROIDAL SAPONINS;16
6.4;STEROIDAL ALKALOIDS;21
6.5;Acknowledgement;35
6.6;References;35
7;CHAPTER 3. ARDENOLIDES AND RELATED PRODUCTS;38
7.1;ABSTRACT;38
7.2;HISTORICAL;38
7.3;MODIFICATIONS OF THE CARDENOLIDE STRUCTURE;42
7.4;References;49
8;CHAPTER 4. CHEMICAL CONTRIBUTIONS TO TAXONOMY AND PHYLOGENY IN THE GENUS ARTEMISIA;52
8.1;ABSTRACT;52
8.2;INTRODUCTION;52
8.3;THE SESQUITERPENE LACTONE CONSTITUENTS;53
8.4;RELATED GENERA OF THE TRIBE;62
8.5;SUMMARY;63
8.6;Acknowledgement;63
8.7;References;64
9;CHAPTER 5. SESQUITERPENES HAVING A FIVE-MEMBERED ETHER-RING IN THE MOLECULE;66
9.1;ABSTRACT;66
9.2;INTRODUCTION;66
9.3;I. OXIDATION OF GUAIOXIDE WITH MICRO-ORGANISMS;67
9.4;II. A NEW FURAN SESQUITERPENE HAVING A CYCLOPROPANE-RING (STRUCTURE OF LINDENENE);70
9.5;III. ON GERMACRANE-TYPE FURAN SESQUITERPENES;77
9.6;IV. SOME CHEMOTAXONOMICAL PROBLEMS;86
9.7;CONCLUSION;88
9.8;References;88
10;CHAPTER 6. APPLICATIONS OF MASS SPECTROMETRY IN THE STEROID FIELD;90
10.1;ABSTRACT;90
10.2;INTRODUCTION;90
10.3;DETERMINATION OF EMPIRICAL FORMULA;91
10.4;STRUCTURE ELUCIDATION OF STEROIDS;92
10.5;Acknowledgement;109
10.6;References;109
11;CHAPTER 7. RECENT ADVANCES IN THE CHEMISTRY OF TERPENOID TUMOR INHIBITORS;112
11.1;ABSTRACT;112
11.2;INTRODUCTION;112
11.3;ISOLATION OF TUMOR-INHIBITORY PRINCIPLES FROM PLANTS;113
11.4;BIOLOGICAL ACTIVITY OF TUMOR-INHIBITORY PRINCIPLES;121
11.5;CONCLUSION;130
11.6;Acknowledgement;130
11.7;References;130
12;CHAPTER 8. ON PHOTOCHEMICAL TRANSFORMATIONS OF STEROIDS;132
12.1;ABSTRACT;132
12.2;INTRODUCTION;132
12.3;PHOTOCHEMICAL CYCLIZATION OF 20- AND 11-OXO STEROIDS
;133
12.4;PHOTOCHEMICAL DECARBONYLATION OF .5-UNSATURATED19-ALDEHYDES;134
12.5;PHOTOCHEMICAL TANSFORMATIONS WITH a,ß-.....- KETONES
;136
12.6;PHOTOSTABILIZATION;145
12.7;Acknowledgement;145
12.8;References;145
13;CHAPTER 9. ADVANCES IN TERPENE CHEMISTRY;148
13.1;ABSTRACT;148
13.2;INTRODUCTION;148
13.3;GUAIANOLIDES;148
13.4;EREMOPHILANOLIDES;153
13.5;FURANO-EREMOPHILANOLIDES;157
13.6;BIOGENESIS OF FURANO-EREMOPHILANOLIDES;166
13.7;Acknowledgement;167
13.8;References;167
14;CHAPTER 10. NEW METHODS OF SPECIFIC FLUORINATION;170
14.1;ABSTRACT;170
14.2;INTRODUCTION;170
14.3;SPECIFIC FLUORINATION OF ORGANIC COMPOUNDS;170
14.4;References;178